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Cancer Immunotherapy
In article number 2103056, Hexiang Deng, Zhi‐Jun Sun, and co‐workers utilize a covalent organic framework with excellent two‐photon absorption (2PA) property as a novel approach to generate photosensitizers for efficient cancer immunotherapy. This is attributed to their high ROS generation capability, which could further induce robust immunogenic cell death and boost antitumor...
Immune checkpoint blockade therapy is revolutionizing the traditional treatment model of multiple tumor types, but remains ineffective for a large subset of patients. Photodynamic therapy (PDT) has been shown to induce cancer cell death and provoke an immune response, and may represent a potential strategy to synergize with immune checkpoint blockade therapy. However, the limited tissue penetration...
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