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The molecular architecture of native GroEL has been studied by solution X-ray scattering. The radius of gyration for the native molecule was estimated to be 66.0 in 50 mM Tris-HCl, 100 mM KCl at pH 7.5 and 25°C. The maximum dimension was estimated to be 170 , based on the pair distance distribution function. A cylindrical structure or two heptameric rings was found to be the best for native...
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