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To estimate the effect of escitalopram (10–20 mg/d) versus placebo for reducing hot flash interference in daily life and understand correlates and predictors of reductions in hot flash interference, a key measure of quality of life.Multisite, randomized, double-blind, placebo-controlled clinical trial.MsFLASH clinical sites in Boston, Indianapolis, Oakland, and Philadelphia.A total of 205 midlife...
The goal of this study was to assess whether menopausal symptoms were more common and/or more severe among women with depressive symptoms.A cross-sectional survey of 1358 women, ages 45–70, at two large integrated health plans (Seattle; Boston) was performed. Information on demographics, medical and reproductive history, medication use, menopausal experience and depressive symptoms (PHQ-8) were collected...
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