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To determine whether single nucleotide polymorphisms (SNPs) of genes coding for matrix metalloproteinases (MMPs) and the prostaglandin F2α receptor gene (PTGFR) are related to a response to latanoprost in a white Spanish population of glaucomatous patients.Case–control study.One hundred twenty-four patients with open-angle glaucoma.Genotyping was performed in 117 patients with primary open-angle glaucoma...
To assess the genetic contribution to proliferative vitreoretinopathy (PVR) and report the strong association observed in the tumor necrosis factor (TNF) locus.As a component of The Retina 4 Project, a case-controlled, candidate gene association study in the TNF locus was conducted.Blood from 450 patients with (138 cases) and without (312 controls) post-rhegmatogenous retinal detachment (RD) PVR was...
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