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Flemingia philippinensis is used as a foodstuff or medicinal plant in the tropical regions of China. The methanol (95%) extract of the roots of this plant showed potent tyrosinase inhibition (80% inhibition at 30μg/ml). Activity-guided isolation yielded six polyphenols that inhibited both the monophenolase (IC 50 =1.01–18.4μM) and diphenolase (IC 50 =5.22–84.1μM) actions of tyrosinase...
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