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Engineering biodegradable nanostructures with precise morphological characteristics is a key objective in nanomedicine. In particular, asymmetric (i.e., nonspherical) nanoparticles are desirable due to the advantageous effects of shape in a biomedical context. Using molecular engineering, it is possible to program unique morphological features into the self‐assembly of block copolymers (BCPs). However,...
The stabilization and transport of low‐solubility drugs, by encapsulation in nanoscopic delivery vectors (nanovectors), is a key paradigm in nanomedicine. However, the problems of carrier toxicity, specificity, and producibility create a bottleneck in the development of new nanomedical technologies. Copolymeric nanoparticles are an excellent platform for nanovector engineering due to their structural...
Amidst the wealth of information that the past few decades of nanomedical research has given us there is one design principle that has emerged as being key for the success of delivery vectors: particle morphology. This review seeks to unpack the various facets of particle morphology that are important for effective integration in vivo. In order to understand the contribution of morphology towards...
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