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In whole body PET scanners, extending the axial field of view (AFOV) can significantly increases the sensitivity. However, image axial resolution, which is an essential criterion in whole-body PET, may be especially affected by the depth of interaction (DOI) as the AFOV increases. In this paper, we use Monte Carlo simulations to find, in a long axial-FOV PET how DOI information affects the axial resolution...
It is known that a reduction of the field-of-view in 3-D X-ray imaging is proportional to a reduction in radiation dose. The resulting truncation, however, is incompatible with conventional reconstruction algorithms. Recently, a novel method for region of interest reconstruction that uses neither prior knowledge nor extrapolation has been published, named approximated truncation robust algorithm for...
System matrix works as an association between image and detected data. Accurate expression of the system matrix is a key component during PET image reconstruction. However, with numerous Line-of-Responses (LORs) detected in modern 3D PET scanner, the huge storage size of a full system matrix increases computational burden. To solve this essential issue, we designed a rotationally symmetric polygonal...
In some clinical applications, e.g., examination of deployed stents or coils during the intervention, only a small portion of the patient may be of diagnostic interest. For the sake of dose reduction to the patient, it is practicable to deploy a collimator to block radiation dose outside volume of interest (VOI). The resulting truncation, however, particularly in lateral direction, poses a challenge...
We developed SPECT imaging capability on an animal PET scanner by placing a slit-slat collimator inside the PET detector gantry. To perform in vivo animal imaging with minimal gravity induced animal motion, we investigated the performance of hybrid rotation-translation (HRT) tomographic scan scheme in this paper. Three evaluation indices, i.e. sampling completeness (SC), sensitivity, and directional...
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