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The thalamus contains two main populations of projection neurons that selectively innervate different elements of the cortical microcircuit: the well-known “specific” or “core” (C-type) cells that innervate cortical layer IV, and, the “matrix” (M-type) cells that innervate layer I. Observations in different mammal species suggest that this may be a conserved, basic organizational principle of thalamocortical...
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