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The development of electroanalytical methods for the detection and quantification of nucleotides in DNA offers vital implications in assessing the degree of oxidation or epigenetic modification in DNA. Unfortunately, the electrochemical response of oligonucleotides is strongly influenced by the size, composition and nucleic base sequence. In this article, an optimized analytical procedure for the...
The determination of 7‐methylguanine (7mG) is an interesting analytical target since its quantification can be correlated with the methylation of cytosine which is one of the most relevant epigenetic modification of DNA. In this work, screen‐printed graphite electrodes were used to study the electrochemical characterization of 7mG by cyclic and square wave voltammetry. 7mG concentration and pH were...
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