Search results for: Wei Liu

Items from 1 to 20 out of 10,258 results

article

The incorporation of KF‐6017 and LiTFSI benefiting for constructing a transparent, highly conductive polydimethylsiloxane‐based ionogel with high‐ionic liquid content

Wei Liu, Shilong Cai, Hefeng Zhang, Yifu Huang

Journal of Applied Polymer Science > 141 > 45 > n/a - n/a

The presence of well‐conductive polydimethylsiloxane (PDMS)‐based ionogel has changed the stereotype of PDMS of being an insulator, owing to continuous ionic liquid (IL) phase with superior ionic conductivity. However, the sacrifice on the transparency of ionogel often occurs if increasing IL content, and to overcome the immiscibility between nonpolar PDMS and polar IL is still regarded as a considerable...

article

High‐Dimensional Overdispersed Generalized Factor Model With Application to Single‐Cell Sequencing Data Analysis

Jinyu Nie, Zhilong Qin, Wei Liu

Statistics in Medicine > 43 > 25 > 4836 - 4849

The current high‐dimensional linear factor models fail to account for the different types of variables, while high‐dimensional nonlinear factor models often overlook the overdispersion present in mixed‐type data. However, overdispersion is prevalent in practical applications, particularly in fields like biomedical and genomics studies. To address this practical demand, we propose an overdispersed...

article

Phenotypic features, prevalence of KCNJ11‐MODY in Chinese patients with early‐onset diabetes and a literature review

Tianhao Ba, Qian Ren, Siqian Gong, Meng Li, more

Clinical Endocrinology > 101 > 5 > 466 - 474

Objective Gain‐of‐function (GOF) variants of KCNJ11 cause neonate diabetes and maturity‐onset diabetes of the young (KCNJ11‐MODY), while loss‐of‐function (LOF) variants lead to hyperinsulinemia hypoglycemia and subsequent diabetes. Given the limited research of KCNJ11‐MODY, we aimed to analyse its phenotypic features and prevalence in Chinese patients with early‐onset type 2 diabetes (EOD). Design,...

article

High‐nitrogen‐induced γ‐aminobutyric acid triggers host immunity and pathogen oxidative stress tolerance in tomato and Ralstonia solanacearum interaction

Wei Liu, Yushu Wang, Tuo Ji, Chengqiang Wang, more

New Phytologist > 244 > 4 > 1537 - 1551

Soil nitrogen (N) significantly influences the interaction between plants and pathogens, yet its impact on host defenses and pathogen strategies via alterations in plant metabolism remains unclear. Through metabolic and genetic studies, this research demonstrates that high‐N‐input exacerbates tomato bacterial wilt by altering γ‐aminobutyric acid (GABA) metabolism of host plants. Under high‐N...

article

Global risk dynamics of Borrelia miyamotoi in the context of climate change

Tian Tang, Hong‐Han Ge, Tian Ma, Meng‐meng Hao, more

Environmental Microbiology > 26 > 10 > n/a - n/a

The impact of Borrelia miyamotoi on human health, facilitated by the expanding geographical distribution and increasing population of Ixodes ticks, remains obscure in the context of global climate change. We employed multiple models to evaluate the effect of global climate change on the risk of B. miyamotoi worldwide across various scenarios. The habitat suitability index of four primary vector tick...

article

Tuning FeO covalency boosts catalytic ozonation over spinel oxide for chemical industrial wastewater decontamination

Xu Cao, Zhao‐Hua Wang, Zhi‐Yan Guo, Si‐Yu Yang, more

AIChE Journal > 70 > 11 > n/a - n/a

Heterogeneous catalytic ozonation (HCO) emerges as a promising chemical industrial wastewater treatment solution, offering enhanced ozone utilization and reduced secondary pollutants. However, challenges in scaling HCO arise from a limited understanding of the catalytic mechanisms of metal oxides, particularly in generating active ozone sites. Here, we demonstrated the improvement of catalytic ozonation...

article

Deep learning in the overall process of implant prosthodontics: A state‐of‐the‐art review

Shunv Ying, Feng Huang, Wei Liu, Fuming He

Clinical Implant Dentistry and Related Research > 26 > 5 > 835 - 846

Artificial intelligence represented by deep learning has attracted attention in the field of dental implant restoration. It is widely used in surgical image analysis, implant plan design, prosthesis shape design, and prognosis judgment. This article mainly describes the research progress of deep learning in the whole process of dental implant prosthodontics. It analyzes the limitations of current...

article

Composition, thermal, and microstructural characteristics of mutton tallows in comparison with beef tallows

Dan Zhang, Tong Wang, Guolong Yang, Jingbo Hu, more

European Journal of Lipid Science and Technology > 126 > 10 > n/a - n/a

The composition, thermal properties, and microstructure of some mutton tallows (MTs), such as sheep tallow (ST), goat tallow (GT), and sheep tail tallow (STT), were investigated and compared with those of beef tallow (BT). The results showed that the fatty acids (FAs) in the MTs were dominated by oleic, stearic, and palmitic acids, which were similar to those of BTs; also there were some natural trans...

article

Rapid Prediction of Energy Level Alignment and Conductance of Single‐Molecule Junctions Through Intramolecular Dipole Moment

Yirong Zhang, Sha Yang, Yang Yang, Ji‐Chang Ren, more

Advanced Functional Materials > 34 > 40 > n/a - n/a

How substituents affect the conductance of single‐molecule junctions has been a subject of ongoing debate. Here, a comparative study on the transport properties across a broader range of experimentally proposed and representative π‐conjugated molecular systems, each characterized by prototypical backbone motifs with distinct terminal groups and featuring a range of substituents is conducted. Employing...

article

One‐Step Organic Synthesis of 18β‐Glycyrrhetinic Acid‐Anthraquinone Ester Products: Exploration of Antibacterial Activity and Structure–Activity Relationship, Toxicity Evaluation in Zebrafish

Zhaoyi Yang, Xueyan Li, Wei Liu, Guangyue Wang, more

Chemical Biology & Drug Design > 104 > 3 > n/a - n/a

To combine the activity characteristics of 18β‐glycyrrhetinic acid (18β‐GA) and anthraquinone compounds (rhein and emodin), reduce toxicity, and explore the structure–activity relationship (SAR) of anthraquinones, 18β‐GA‐anthraquinone ester compounds were synthesized by one‐step organic synthesis. The products were separated and purified by HPLC and characterized by NMR and EI‐MS. It was finally determined...

article

A Generalized Coordination Engineering Strategy for Single‐Atom Catalysts toward Efficient Hydrogen Peroxide Electrosynthesis

Wei Liu, Rui Chen, Zhiyuan Sang, Zhenxin Li, more

Advanced Materials > 36 > 38 > n/a - n/a

Designing non‐noble metal single‐atom catalysts (M‐SACs) for two‐electron oxygen reduction reaction (2e‐ORR) is attractive for the hydrogen peroxide (H₂O₂) electrosynthesis, in which the coordination configuration of the M‐SACs essentially affects the reaction activity and product selectivity. Though extensively investigated, a generalized coordination engineering strategy has not yet been proposed,...

article

Cascade C−H Activation and Two C−C Bond Forming in Reaction of Azalutetacyclopentadiene with 2‐Methylbenzonitriles

Zhengqi Chai, Ze‐Jie Lv, Wei Liu, Jinxiao Yang, more

Chemistry – A European Journal > 30 > 53 > n/a - n/a

Azametallacyclopentadienes are an important class of metallacycles as the key intermediates in metal‐promoted or catalyzed carbon‐carbon coupling reaction of nitriles and alkynes. Rare‐earth azametallacyclopentadienes have shown various reactivity toward nitriles, depending on the substituents of nitriles. The reaction of azalutetacyclopentadienes toward 2‐methylbenzonitriles has been investigated...

article

Degradation of sesame hull pectin during roasting: catalytic effects of four inorganic chloride salts

Chuan‐Lei Zheng, Zhi Qin, Kun‐Qi Wang, Tian‐Tian Gao, more

International Journal of Food Science & Technology > 59 > 10 > 7487 - 7496

Sesame seed hull contains a substantial concentration of minerals. During the roasting, these minerals assume a catalytic function in the degradation of the sesame seed hull pectin. In this work, the effect of four inorganic chloride salts on the structure and thermal degradation products of sesame hull pectin during heating was investigated. The results indicated that, during roasting, chloride salts...

article

Composition of sesame hull oil and its effects on flavour and quality of sesame oil

Rui Wang, Bing‐Xin Guo, Xiao‐Yu Li, Jin‐Qiao Peng, more

International Journal of Food Science & Technology > 59 > 10 > 6987 - 6998

In this study, sesame hull oil (SHO) was extracted to characterise its composition. SHO was heated to determine the volatiles and their effect on the quality of cold‐pressed dehulled sesame oil (SO). Seventeen fatty acids, four lignans (1088.65 mg/100 g), tocopherols (284.17 mg/100 g) mainly in the γ‐form, and sterol (1722.16 mg/100 g, 4.67 times more than in sesame kernel oil) were detected in SHO...

article

Discovery of Sesquiterpene Lactones with Cytotoxicity from the Herb of Youngia japonica

Xian‐Sheng Ye, Kuan Lin, Xiao‐Qing Tao, Jin‐Ting Shang, more

Chemistry & Biodiversity > 21 > 9 > n/a - n/a

In the process of searching for anti‐breast cancer agents, five sesquiterpene lactones (1‐5), including two previously undescribed ones, yjaponica B‐C (1‐2), were isolated from the herb of Youngia japonica. Their structures were elucidated by spectroscopic data analyses and Marfey's method. Cytotoxic activities of all compounds against A549, U87, and 4T1 cell lines were tested using the CCK8 assay...

article

Cover Image

Qun Zhou, Siqi Gao, Xiaohan Yu, Linzhang Zhang, more

Phytotherapy Research > 38 > 9 > i - i

The cover image is based on the article Total astragalus saponins attenuate primary sclerosing cholangitis in mice by upregulation of TGR5 by Qun Zhou et al., https://doi.org/10.1002/ptr.8297.

article

Total astragalus saponins attenuate primary sclerosing cholangitis in mice by upregulation of TGR5

Qun Zhou, Siqi Gao, Xiaohan Yu, Linzhang Zhang, more

Phytotherapy Research > 38 > 9 > 4502 - 4518

Total astragalus saponins (TAS) are the main active components of astragali radix, and have potent anti‐hepatic fibrosis effect. However, the therapeutic efficacy of TAS and their potential mechanisms in the treatment of primary sclerosing cholangitis (PSC) remain unclear. In this study, two mouse models of PSC, including 3,5‐Diethoxycarbonyl‐1,4‐Dihydro‐2,4,6‐Collidine (DDC)‐induced PSC and Mdr2^−/−...

article

Golgi protein ACBD3 downregulation sensitizes cells to ferroptosis

Ying Qian, Shanchuan Ma, Rong Qiu, Zhiyang Sun, more

Cell Biology International > 48 > 10 > 1559 - 1572

Ferroptosis, a form of cell death driven by iron‐dependent lipid peroxidation, is emerging as a promising target in cancer therapy. It is regulated by a network of molecules and pathways that modulate lipid metabolism, iron homeostasis and redox balance, and related processes. However, there are still numerous regulatory molecules intricately involved in ferroptosis that remain to be identified. Here,...

article

Commitment of human mesenchymal stromal cells towards ACL fibroblast differentiation upon rAAV‐mediated FGF‐2 and TGF‐β overexpression using pNaSS‐grafted PCL films

Meret Stehle, Mahnaz Amini, Jagadeesh K. Venkatesan, Wei Liu, more

Biotechnology and Bioengineering > 121 > 10 > 3196 - 3210

Despite various clinical options, human anterior cruciate ligament (ACL) lesions do not fully heal. Biomaterial‐guided gene therapy using recombinant adeno‐associated virus (rAAV) vectors may improve the intrinsic mechanisms of ACL repair. Here, we examined whether poly(sodium styrene sulfonate)‐grafted poly(ε‐caprolactone) (pNaSS‐grafted PCL) films can deliver rAAV vectors coding for the reparative...

article

The totipotent 2C‐like state safeguards genomic stability of mouse embryonic stem cells

Zeling Du, Meiqi Lin, Qiaohua Li, Dan Guo, more

Journal of Cellular Physiology > 239 > 9 > n/a - n/a

Mouse embryonic stem cells (mESCs) sporadically transition to a transient totipotent state that resembles blastomeres of the two‐cell (2C) embryo stage, which has been proposed to contribute to exceptional genomic stability, one of the key features of mESCs. However, the biological significance of the rare population of 2C‐like cells (2CLCs) in ESC cultures remains to be tested. Here we generated...

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INFONA - science communication portal

Search results for: Wei Liu

The incorporation of KF‐6017 and LiTFSI benefiting for constructing a transparent, highly conductive polydimethylsiloxane‐based ionogel with high‐ionic liquid content

High‐Dimensional Overdispersed Generalized Factor Model With Application to Single‐Cell Sequencing Data Analysis

Phenotypic features, prevalence of KCNJ11‐MODY in Chinese patients with early‐onset diabetes and a literature review

High‐nitrogen‐induced γ‐aminobutyric acid triggers host immunity and pathogen oxidative stress tolerance in tomato and Ralstonia solanacearum interaction

Global risk dynamics of Borrelia miyamotoi in the context of climate change

Tuning FeO covalency boosts catalytic ozonation over spinel oxide for chemical industrial wastewater decontamination

Deep learning in the overall process of implant prosthodontics: A state‐of‐the‐art review

Composition, thermal, and microstructural characteristics of mutton tallows in comparison with beef tallows

Rapid Prediction of Energy Level Alignment and Conductance of Single‐Molecule Junctions Through Intramolecular Dipole Moment

One‐Step Organic Synthesis of 18β‐Glycyrrhetinic Acid‐Anthraquinone Ester Products: Exploration of Antibacterial Activity and Structure–Activity Relationship, Toxicity Evaluation in Zebrafish

A Generalized Coordination Engineering Strategy for Single‐Atom Catalysts toward Efficient Hydrogen Peroxide Electrosynthesis

Cascade C−H Activation and Two C−C Bond Forming in Reaction of Azalutetacyclopentadiene with 2‐Methylbenzonitriles

Degradation of sesame hull pectin during roasting: catalytic effects of four inorganic chloride salts

Composition of sesame hull oil and its effects on flavour and quality of sesame oil

Discovery of Sesquiterpene Lactones with Cytotoxicity from the Herb of Youngia japonica

Cover Image

Total astragalus saponins attenuate primary sclerosing cholangitis in mice by upregulation of TGR5

Golgi protein ACBD3 downregulation sensitizes cells to ferroptosis

Commitment of human mesenchymal stromal cells towards ACL fibroblast differentiation upon rAAV‐mediated FGF‐2 and TGF‐β overexpression using pNaSS‐grafted PCL films

The totipotent 2C‐like state safeguards genomic stability of mouse embryonic stem cells

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