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The global increase in obesity, along with the associated adverse health consequences, has heightened interest in the fundamental causes of excessive weight gain. Attributing obesity to “gluttony and sloth”, blaming the obese for overeating and limiting physical activity, oversimplifies a complex problem, since substantial differences in metabolic efficiency between lean and obese have been decisively...
While fasting suppresses sympathetic nervous system (SNS) activity in most peripheral tissues, the response of sympathetic nerves in white adipose tissue (WAT) is reportedly stimulatory. To confirm this finding and to determine if the fasting response in WAT is susceptible to developmental modification, SNS activity was compared in fed and fasted animals using techniques of [ 3 H]norepinephrine...
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