Search results for: Chi-Tang Ho

Items from 1 to 20 out of 368 results

article

Crucial textural properties of braised pork to evaluate the oral mastication behavior and its water distribution to influence tenderness

Xiaomin Wang, Meigui Huang, Yishun Yao, Jingyang Yu, more

Journal of Food Science > 89 > 10 > 6174 - 6188

Abstract The complex composition of braised pork, including lean meat, pigskin, and fat, makes it difficult for sensory evaluation of its texture properties. This study investigated the correlation between sensory texture attributes and physicochemical properties to achieve an objective and comprehensive evaluation of the texture of braised pork. Sensory analysis demonstrated that the overall texture...

article

Hepatoprotective effect of dietary pterostilbene against high‐fat‐diet‐induced lipid accumulation exacerbated by chronic jet lag via SIRT1 and SIRT3 activation

Yen‐Chun Koh, Ching‐Hui Yao, Pei‐Sheng Lee, Kalyanam Nagabhushanam, more

Phytotherapy Research > 38 > 8 > 4099 - 4113

Hepatic lipid metabolism is modulated by the circadian rhythm; therefore, circadian disruption may promote obesity and hepatic lipid accumulation. This study aims to investigate dietary pterostilbene (PSB) ‘s protective effect against high‐fat‐diet (HFD)‐induced lipid accumulation exacerbated by chronic jet lag and the potential role of gut microbiota therein. Mice were treated with a HFD and chronic...

article

Berry anthocyanins prevent α‐dicarbonyls and advanced glycation end product formation in phosphate‐buffered saline‐based model systems, cookie and ground pork

Yu‐Wen Hsiao, Shih‐Min Hsia, Min‐Hsiung Pan, Chi‐Tang Ho, more

Journal of Food Science > 89 > 6 > 3745 - 3758

Abstract α‐Dicarbonyls and advanced glycation end products (AGEs) are the heat‐induced potential toxicants commonly found in thermally processed foods due to the Maillard reaction. Research has shown that both α‐dicarbonyls and AGEs can cause oxidative stress and inflammation and have a positive link with several chronic diseases, such as diabetes. This study found that commonly consumed berry fruits...

article

3′‐Hydroxypterostilbene Potently Suppresses Tumor Growth via Inhibiting the Activation of the JAK2/STAT3 Pathway in Ovarian Clear Cell Carcinoma

Yen‐Chun Koh, Wei‐Zhe Huang, Kalyanam Nagabhushanam, Chi‐Tang Ho, more

Molecular Nutrition & Food Research > 68 > 1 > n/a - n/a

Scope Ovarian clear cell carcinoma (OCCC) is a subtype of epithelial ovarian cancer (EOC) that is associated with higher interleukin‐6 (IL‐6) levels, and suppression of the Janus kinase 2/Signal transducer and activator of transription 3 (JAK2/STAT3) pathway may contribute to the suppression of this cancer. This study aims to compare the anti‐cancer effect of pterostilbene (PSB) and 2’‐ and 3’‐hydroxypterostilbene...

article

Pterostilbene Enhances Thermogenesis and Mitochondrial Biogenesis by Activating the SIRT1/PGC‐1α/SIRT3 Pathway to Prevent Western Diet‐Induced Obesity

Yen‐Chun Koh, Shin‐Jhih Lin, Kai‐Yu Hsu, Kalyanam Nagabhushanam, more

Molecular Nutrition & Food Research > 67 > 18 > n/a - n/a

Scope Sirtuin 1/peroxisome proliferator‐activated receptor gamma co‐activator 1 alpha (SIRT1/PGC‐1α) pathway activation is known to promote thermogenesis and mitochondrial biogenesis. Pterostilbene (PSB) and pinostilbene (PIN), the methylated analogs of resveratrol, are potential candidates to enhance thermogenesis and mitochondrial biogenesis. Method and results A model of Western diet‐induced...

article

Prevention of Glutamate‐Induced Neurodegeneration by Piceatannol via Mitochondrial Rescue In Vitro and In Vivo

Yen‐Chun Koh, Dickson Chok, Chun‐Han Chang, Chia‐Cheng Wei, more

Molecular Nutrition & Food Research > 67 > 13 > n/a - n/a

Scope Parkinson's disease is one of the neurodegenerative diseases that have no cure. Excitotoxicity induced by excess glutamate is known to be a hallmark of these diseases. Therefore, this study aims to evaluate the preventive effect of piceatannol on glutamate‐induced neurodegeneration via mitochondrial rescue. Methods and results The PC12 cell line and three Caenorhabditis elegans (C. elegans...

article

Effect of heat‐treating methods on components, instrumental evaluation of color and taste, and antioxidant properties of sea buckthorn pulp flavonoids

Ran Liu, Yunning Yang, Menghan Zhao, Yanqun Wang, more

Journal of Food Science > 87 > 12 > 5442 - 5454

Abstract Sea buckthorn has strong physiological activities, which might be attributed to its flavonoid compounds. The heat treatment could speed up the transformation of the flavonoids, so it would affect the properties of the flavonoids. To explore the effect of the heat‐treating methods on the sea buckthorn pulp flavonoids, the flavonoid compositions, color and taste properties, and antioxidant...

article

Development and application of edible coating on dried pineapple exposed to electrical blanching

Jia‐Jing He, Chun‐Hui Chiu, Mohsen Gavahian, Chi‐Tang Ho, more

Journal of Food Processing and Preservation > 46 > 8 > n/a - n/a

A new edible coating was developed based on pectin and honey at various ratios with or without blanching pretreatment, which was done by an emerging thermal technology. The results showed that the water activity and the total bacterial count were the lowest in samples coated by a combination of pectin + honey as compared with the control group, indicating the former's effectiveness in improving the...

article

The Anti‐Obesity and Anti‐Inflammatory Capabilities of Pterostilbene and its Colonic Metabolite Pinostilbene Protect against Tight Junction Disruption from Western Diet Feeding

Yen‐Chun Koh, Shin‐Jhih Lin, Kalyanam Nagabhushanam, Chi‐Tang Ho, more

Molecular Nutrition & Food Research > 66 > 16 > n/a - n/a

Scope Tight junctions (TJs) are a member of the intestinal epithelium barrier that provides the first line of protection against external factors. Anti‐obesity and protective effects of pterostilbene (PSB) on TJs have previously been reported, but the effect of its colonic metabolite, pinostilbene (PIN), is less understood. Methods and results A 16‐week animal model feed with western‐diet to induce...

article

S‐Allylcysteine Potently Protects against PhIP‐Induced DNA Damage via Nrf2/AhR Signaling Pathway Modulation in Normal Human Colonic Mucosal Epithelial Cells

Wei‐Sheng Lin, Ying‐Jang Lai, Kalyanam Nagabhushanam, Chi‐Tang Ho, more

Molecular Nutrition & Food Research > 66 > 16 > n/a - n/a

Scope This study aims to investigate whether S‐allylcysteine (SAC) exerts chemoprophylactic effects on foodborne carcinogenicity caused by 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP) in normal human colonic mucosal epithelial cells. Methods and results Cellular thermal shift assays show that SAC has an affinity for the Kelch‐like ECH‐associated protein 1 (Keap1) protein. Moreover, SAC...

article

Piceatannol Prevents Colon Cancer Progression via Dual‐Targeting to M2‐Polarized Tumor‐Associated Macrophages and the TGF‐β1 Positive Feedback Signaling Pathway

Yi‐Shiou Chiou, Yi‐Ming Lan, Pei‐Sheng Lee, Qianyu Lin, more

Molecular Nutrition & Food Research > 66 > 15 > n/a - n/a

Scope M2 phenotype tumor‐associated macrophages (M2‐TAMs) play a key role in distant metastasis and poor clinical outcomes. Herein, a specific molecular mechanism that contributes to malignant progression is illuminated and investigates whether piceatannol (PIC) can target the crosstalk between M2‐TAMs and cancer cells for potential colorectal cancer (CRC) therapy. Methods and results To mimic...

article

Review on chemical compositions and biological activities of peanut (Arachis hypogeae L.)

Li Mingrou, Sen Guo, Chi‐Tang Ho, Naisheng Bai

Journal of Food Biochemistry > 46 > 7 > n/a - n/a

Peanut (Arachis hypogeae L.) is a food resource with great nutritional and health functions. The present review summarized the nutrients (proteins, lipids, carbohydrates, vitamins, and minerals), chemical components (stilbenoids, flavonoids, phenolic acids, phytosterols, triterpenes, and alkaloids), and biological activities of edible parts of peanut, and research value of bioactive factor resveratrol...

article

Ziziphi Spinosae Semen: An updated review on pharmacological activity, quality control, and application

Dongdong Wang, Chi‐Tang Ho, Naisheng Bai

Journal of Food Biochemistry > 46 > 7 > n/a - n/a

Ziziphi Spinosae Semen (the dried seeds of Ziziphus jujuba Mill. var. spinosa, Rhamnaceae) is a well‐known traditional Chinese medicine (TCM) with high edible and pharmaceutical value. It contains abundant phytochemicals and possesses multiple biological activities. Phytochemicals include saponins, flavonoids, alkaloids, fatty acids, and others. Among them, saponins and flavonoids are considered...

article

S‐Allylcysteine Ameliorates Aging Features via Regulating Mitochondrial Dynamics in Naturally Aged C57BL/6J Mice

Pin‐Hua Chen, Chun‐Han Chang, Wei‐Sheng Lin, Kalyanam Nagabhushanam, more

Molecular Nutrition & Food Research > 66 > 7 > n/a - n/a

Scope S‐Allylcysteine (SAC) is the most abundant organosulfur molecule derived from aged garlic. The effects ofSAC on improving Aging in naturally aged C57BL/6J male mice and mitochondrial dynamics in Caenorhabditis elegans and its underlying mechanisms is evaluated. Methods and Results When mice have attained reproductive senescence at 60 weeks of age, SAC is supplemented to 0.05% and 0.2% into...

article

Dietary Pterostilbene and Resveratrol Modulate the Gut Microbiota Influenced by Circadian Rhythm Dysregulation

Yen‐Chun Koh, Pei‐Sheng Lee, Yu‐Lun Kuo, Kalyanam Nagabhushanam, more

Molecular Nutrition & Food Research > 65 > 21 > n/a - n/a

Scope A causal relationship between circadian misalignment and microbiota dysbiosis has been discussed recently, due to their association to pathogenesis. Herein, the possible impact of pterostilbene (PSB) and resveratrol (RES) on the gut microbiota brought by chronic jet‐lag in mice is investigated. Methods and Results Dietary supplement of RES and PSB (0.25%) are given to 16 week‐jetlagged mice...

article

CSC‐3436 sensitizes triple negative breast cancer cells to TRAIL‐induced apoptosis through ROS‐mediated p38/CHOP/death receptor 5 signaling pathways

Chun‐Chen Huang, Yi‐Ching Cheng, Ying‐Chao Lin, Chun‐Hung Chou, more

Environmental Toxicology > 36 > 12 > 2578 - 2588

Tumor necrosis factor‐related apoptosis‐induced ligand (TRAIL) shows little or no toxicity in most normal cells and preferentially induces apoptosis in a variety of malignant cells. However, patients develop resistance to TRAIL, therefore, sensitizing agents that can sensitize the tumor cells to TRAIL‐mediated apoptosis are necessary. In this study, we investigated the effect of 2‐(3‐hydroxyphenyl)‐5‐methylnaphthyridin‐4‐one...

article

Demethoxycurcumin induces apoptosis in HER2 overexpressing bladder cancer cells through degradation of HER2 and inhibiting the PI3K/Akt pathway

Chien‐Chang Kao, Yi‐Ching Cheng, Ming‐Hsin Yang, Tai‐Lung Cha, more

Environmental Toxicology > 36 > 11 > 2186 - 2195

Bladder cancer is the most common malignancy of the urinary tract and arising from the epithelial lining of the urinary bladder. Resistance to cytotoxic therapies is associated with overexpression of oncogenic proteins; including HER2, and Akt in chemotherapy resistance of bladder cancer. Various studies demonstrated that curcuminoids, the most important active phenolic compounds of turmeric (Curcuma longa...

article

Inhibitory Effect of Garcinol on Obesity‐Exacerbated, Colitis‐Mediated Colon Carcinogenesis

Pei‐Sheng Lee, Kalyanam Nagabhushanam, Chi‐Tang Ho, Min‐Hsiung Pan

Molecular Nutrition & Food Research > 65 > 17 > n/a - n/a

Scope Epidemiological studies show a consistent and compelling association between the risk of colorectal cancer development and obesity, but its mechanisms remain poorly understood. Evidence is mounting that colorectal cancer can be prevented by nutritional supplements, such as phytochemicals. Garcinol, a polyisoprenylated benzophenone derivative, is widely present in Garcinia plants. This study...

article

Dietary strategies may influence human nerves and emotions by regulating intestinal microbiota: an interesting hypothesis

Mengyu Hong, Chi‐Tang Ho, Xin Zhang, Ruilin Zhang, more

International Journal of Food Science & Technology > 56 > 7 > 3311 - 3321

The human body hosts enormous diversity of microbiota. Recently, the importance of microbial communities to host physiology has been recognised. Evidence is now emerging that the bidirectional communication between the central nervous system and gastrointestinal tract may affect human nerves, cognition and behaviour through the gut‐brain axis (GBA). Although the connection between enteropathy and...

article

Yellow Tea Stimulates Thermogenesis in Mice through Heterogeneous Browning of Adipose Tissues

Na Xu, Jun Chu, Rongrong Dong, Fengjuan Lu, more

Molecular Nutrition & Food Research > 65 > 2 > n/a - n/a

Scope Large‐leaf yellow tea (YT) exhibits interesting beneficial metabolic effects in previous studies. Here, the authors elucidated the actions of YT on thermogenesis, energy metabolism, and adipocyte metabolic conversion. Methods and Results Five‐week‐old male C57BL/6 mice are fed low‐fat diet, high‐fat diet (HFD), and HFD supplemented with 0.5% or 2.5% YT. After treatment for 10 or 14 weeks,...

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INFONA - science communication portal

Search results for: Chi-Tang Ho

Crucial textural properties of braised pork to evaluate the oral mastication behavior and its water distribution to influence tenderness

Hepatoprotective effect of dietary pterostilbene against high‐fat‐diet‐induced lipid accumulation exacerbated by chronic jet lag via SIRT1 and SIRT3 activation

Berry anthocyanins prevent α‐dicarbonyls and advanced glycation end product formation in phosphate‐buffered saline‐based model systems, cookie and ground pork

3′‐Hydroxypterostilbene Potently Suppresses Tumor Growth via Inhibiting the Activation of the JAK2/STAT3 Pathway in Ovarian Clear Cell Carcinoma

Pterostilbene Enhances Thermogenesis and Mitochondrial Biogenesis by Activating the SIRT1/PGC‐1α/SIRT3 Pathway to Prevent Western Diet‐Induced Obesity

Prevention of Glutamate‐Induced Neurodegeneration by Piceatannol via Mitochondrial Rescue In Vitro and In Vivo

Effect of heat‐treating methods on components, instrumental evaluation of color and taste, and antioxidant properties of sea buckthorn pulp flavonoids

Development and application of edible coating on dried pineapple exposed to electrical blanching

The Anti‐Obesity and Anti‐Inflammatory Capabilities of Pterostilbene and its Colonic Metabolite Pinostilbene Protect against Tight Junction Disruption from Western Diet Feeding

S‐Allylcysteine Potently Protects against PhIP‐Induced DNA Damage via Nrf2/AhR Signaling Pathway Modulation in Normal Human Colonic Mucosal Epithelial Cells

Piceatannol Prevents Colon Cancer Progression via Dual‐Targeting to M2‐Polarized Tumor‐Associated Macrophages and the TGF‐β1 Positive Feedback Signaling Pathway

Review on chemical compositions and biological activities of peanut (Arachis hypogeae L.)

Ziziphi Spinosae Semen: An updated review on pharmacological activity, quality control, and application

S‐Allylcysteine Ameliorates Aging Features via Regulating Mitochondrial Dynamics in Naturally Aged C57BL/6J Mice

Dietary Pterostilbene and Resveratrol Modulate the Gut Microbiota Influenced by Circadian Rhythm Dysregulation

CSC‐3436 sensitizes triple negative breast cancer cells to TRAIL‐induced apoptosis through ROS‐mediated p38/CHOP/death receptor 5 signaling pathways

Demethoxycurcumin induces apoptosis in HER2 overexpressing bladder cancer cells through degradation of HER2 and inhibiting the PI3K/Akt pathway

Inhibitory Effect of Garcinol on Obesity‐Exacerbated, Colitis‐Mediated Colon Carcinogenesis

Dietary strategies may influence human nerves and emotions by regulating intestinal microbiota: an interesting hypothesis

Yellow Tea Stimulates Thermogenesis in Mice through Heterogeneous Browning of Adipose Tissues

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