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Driveline exit site (DLES) infection is a major complication of ventricular assist devices (VADs). Differences in the sheath material interfacing with exit site tissue appear to affect healing time and infection risk more than site hygiene, but the mechanistic basis for this is not clear.Health record data from Utah Artificial Heart Program patients with HeartMate II (HMII) devices implanted from...
Antibody-mediated rejection (AMR) of cardiac allografts is associated with reduced long-term graft survival, but not every patient with AMR develops premature graft failure. The tissue level mechanisms leading to graft failure in some patients with antibody-mediated rejection are poorly characterized.We assessed changes in myocardial microvessel density (number of capillaries per unit area) in endomyocardial...
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