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Sex-specific differences in pulmonary morbidity in adults and preterm infants are well documented. Hyperoxia contributes to lung injury in experimental animals and humans. Cytochrome P450 (CYP) 1A enzymes have been shown to play a mechanistic role in hyperoxic lung injury (HLI) in animal models. Whether CYP1A enzymes contribute to gender-specific differences in relation to HLI is unknown. In this...
We reported the studies of aggregation, cellular uptake and cytotoxicity of C 60 (OH) x , one of important water-soluble fullerene derivatives. The results showed C 60 (OH) x was smaller in size but harder to go into cells in the media with serum. Moreover, C 60 (OH) x showed severe toxicity to Chinese hamster lung and Chinese hamster ovary cells, but...
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