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Gout results from elevated urate concentrations in the blood (hyperuricaemia). When super-saturation of urate is reached, monosodium urate crystals form within the joint. In some individuals, these crystals elicit a painful self-limiting inflammatory response that is characteristic of acute gouty arthritis. The most important cause of hyperuricaemia is reduced excretion of uric acid in the urine....
La goutte résulte d’une augmentation des concentrations d’acide urique dans le sang (hyperuricémie). Quand une sursaturation en urates est atteinte, des cristaux d’urate monosodique se forment dans l’articulation. Chez certains individus, ces cristaux provoquent une réponse inflammatoire douloureuse auto-limitée, caractéristique de la crise de goutte aiguë. La plus importante cause d’hyperuricémie...
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