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The influence of genes on cortical structures has been assessed through various phenotypes already. However, the heritability of the sulcal pits, which are the deepest points of the sulci, has not yet been estimated. These pits are assumed to be under tight genetic control and to have close relationship with underlying functional organization. We estimated the heritability of these pits depth using...
The promise of Alzheimer’s disease biomarkers has led to their incorporation in new diagnostic criteria and in therapeutic trials; however, significant barriers exist to widespread use. Chief among these is the lack of internationally accepted standards for quantitative metrics. Hippocampal volumetry is the most widely studied quantitative magnetic resonance imaging measure in Alzheimer’s disease...
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