The problems of modern scientific researches in the aspect of the peculiarities of the use of information and communication educational space in a higher educational institution for the organization of pedagogical interaction are researched. The pedagogical conditions for increasing the efficiency of pedagogical interaction of the participants of the educational process in the conditions of functioning of information and communication educational spaces in the higher educational institution: pedagogical activity of teachers; informational competence of participants in pedagogical interaction; pedagogical monitoring of the quality of professional training of specialists; organization of social and psychological comfort of educational activity. The criteria of the effectiveness of the pedagogical interaction of the participants in the educational process in the conditions of the functioning of the ICLS of the higher educational institution are determined: motivational, cognitive, cooperation, and the corresponding levels of pedagogical interaction efficiency: high, sufficient and low. The results of the pedagogical experiment on the confirmation of the effectiveness of the isolated pedagogical conditions for improving the effectiveness of the organization of pedagogical interaction in the conditions of the functioning of the information and communication educational space of the higher educational institution are presented.