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A newly emerged H7N9 influenza virus isolated from poultry and humans in China. Its nonpathogenic nature in poultry enables avian H7N9 virus replicate silently in avian species, transmit to humans and become more virulent and transmissible in the human population. Eritoran, a potent, well tolerated, synthetic TLR4 antagonist blocks influenza-induced lethality in mice, as well as lung pathology, clinical...
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