The authors examined the influence of narcissism and social desirability on hostility in two samples of 215 college students and 30 patients with myocardial infarction (MI). Results were as follows: (1) MI patients had stronger cynical hostility and lower social desirability than college students; (2) hostility was related to narcissism before and after controlling for social desirability in both MI patients and college students; and (3) these tendencies were stronger in MI patients than in college students, although there were no significant differences.