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Objective: To investigate insulin metabolism and its modifications induced by the administration of flutamide, a specific antiandrogen compound, in women with idiopathic hirsutism (IH) and in nonobese women with polycystic ovary syndrome (PCOS).Design: Prospective, randomized trial.Setting: Endocrinological Centre of the Department of Obstetrics and Gynecology, University of Caligari, Caligari, Italy...
Objective: To evaluate whether, by blocking androgen action, flutamide can decrease and normalize vascular resistance in the uterine artery in patients with polycystic ovary syndrome (PCOS).Design: Prospective and controlled study.Setting: Endocrinological Centre of the Department of Obstetrics and Gynecology of the University of Cagliari, Italy.Patient(s): Twenty-two patients with PCOS were enrolled...
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