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To identify human spermatogenesis-related proteins.Prospective study.University research laboratory.Three fertile men with normal spermatogenesis, 3 azoospermic patients with sloughing and disorganization of germ cells.Testicular tissue samples were collected by biopsy after informed consent.The protein expressional profiles of human testes of fertile men and azoospermic patients were compared using...
To determine whether the transcription factors liver X receptors (LXRs) and their downstream genes, which are involved in the regulation of several testicular functions in mouse models, are differentially expressed in testes of men with nonobstructive azoospermia (NOA) or obstructive azoospermia (OA).Prospective study.University hospital.Patients with various types of NOA (n = 22) and with OA (n =...
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