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Recent evidence has demonstrated that N-methyl-d-aspartic acid (NMDA) and non-NMDA, excitatory amino acid (EAA) receptor antagonists block the motor stimulating, neurotoxic, and rewarding actions of cocaine and the amphetamines. The participants in this symposium discussed evidence that (i) the initiation of stimulant-induced behavioral sensitization involves NMDA receptor stimulation in the ventral...
To review the thermal effects of MDMA in humans, and discuss the practical implications.The literature on Ecstasy/MDMA, body temperature, and subjective thermal self-ratings was reviewed, and explanatory models for the changes in thermal homeostasis were examined and debated.In human placebo-controlled laboratory studies, the effects of MDMA were dose related. Low doses had little effect, moderate...
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