Monthly methane concentration (CH4) level over Zoige alpine wetland, China from October of 2002 to December of 2006 was analyzed based on the SCIAMACHY data. The level was low and might decrease from January to March then increase until August (except for 2006), and then decreased until fall or early winter. The linkage of the CH4, air temperature, precipitation, and soil temperature and moisture content was then explored by using meteorological and GLDAS datasets. The CH4 emission and concentration level in the vertical column over the wetland could be affected more by the temperature than the precipitation.