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An epiretinal prosthesis aims to restore functional vision in patients suffering from retinal degeneration caused by diseases such as Retinitis Pigmentosa (RP) and Age-Related Macular Degeneration (AMD). These diseases result in the loss of photoreceptors but bipolar, amacrine and ganglion cells survive at high rates and can be electrically activate to produce the sensation of light. Continuous application...
Brain is an electrochemical system and recent studies suggest simultaneous measurement of interrelated brain's electrical and neurochemical activity may lead to better understanding of brain function in addition to developing optimal neural prosthetics. By exploiting opamp Time-sharing technique to minimized power dissipation and silicon area, we have fabricated a power efficient implantable CMOS...
We previously proposed a new bioinstrumentation using the shape deformation of the amputated upper limbs without using the myoelectricity generated on the skin of the upper limbs. However many electronic parts were required owing to a bridge circuit and multi-amplifier circuits so as to amplify a tiny voltage of strain gages. Moreover, the surplus heat might occur by the overcurrent owing to low resistance...
During physiological gait, humans continuously modulate their knee stiffness, depending on the demands of the activity and the terrain. A similar functionality could be provided by modern actuators in transfemoral prosthesis. However, quantitative data on how knee stiffness is modulated during physiological gait is still missing. This is likely due to the experimental difficulties associated with...
By design, commonly worn energy storage and release (ESR) prosthetic feet cannot provide biologically realistic ankle joint torque and angle profiles during walking. Additionally, their anthropomorphic, cantilever architecture causes their mechanical stiffness to decrease throughout the stance phase of walking, opposing the known trend of the biological ankle. In this study, the design of a quasi-passive...
This paper presents simulations of a new type of powered ankle prosthesis designed to dynamically align the tibia with the ground reaction force (GRF) vector during peak loading. The functional goal is to reduce the moment transferred through the socket to the soft tissue of the residual limb. The forward dynamics simulation results show a reduction in socket moment and the impact on the pelvis and...
We previously proposed a passive mechanism as the link knee joint unit (LKJ) for a transfemoral prosthesis for stair ascent. The prototype allowed the experimental subjects to ascend stairs without the use of a handrail. In the present study, we modified the LKJ unit and developed further two designs of the LKJ unit. One has full knee extension function during the prosthetic stance phase (condition...
Although great advances have been made in the design and control of lower extremity prostheses, walking on different terrains, such as ramps or stairs, and transitioning between these terrains remains a major challenge for the field. In order to generalize biomimetic behaviour of active lower-limb prostheses top-down volitional control is required but has until recently been deemed unfeasible due...
People with degenerative retinal diseases such as retinitis pigmentosa lose most of their photoreceptors but retain a significant proportion (∼30%) of their retinal ganglion cells (RGCs). Microelectronic retinal prostheses aim to bypass the lost photoreceptors and restore vision by directly stimulating the surviving RGCs. Here we investigate the extent to which electrical stimulation of RGCs can evoke...
Image processing can improve significantly the every-day life of blind people wearing current and upcoming retinal prostheses relying on an external camera. We propose to use a real-time text localization algorithm to improve text accessibility. An augmented text-specific rendering based on automatic text localization has been developed. It has been evaluated in comparison to the classical rendering...
Despite modern technological advances, the most widely available prostheses provide little functional recovery beyond basic grasping. Although sophisticated upper extremity prostheses are available, optimal prosthetic interfaces which give patients high-fidelity control of these artificial limbs are limited. We have developed a novel Regenerative Peripheral Nerve Interface (RPNI), which consists of...
We present a novel swing phase controller for powered transfemoral prostheses based on minimum jerk theory. The proposed controller allows physiologically appropriate swing movement at any walking speed, regardless of the stance controller action. Preliminary validation in a transfemoral amputee subject demonstrates that the proposed controller provides physiological swing timing, without speed-or...
Lightweight prostheses are preferred in terms of usability in daily living. However, this is not a property easy to realize, especially for shoulder prostheses. High portability, multiple degrees of freedom (DOFs) with an appropriate ROM (range of motion), sufficient end-effector power, and suitable viscoelasticity for the safe use in daily living, usually result in a heavy weight. In this paper,...
Recently developed powered prostheses are capable of producing near-physiological joint torque at the knee and/or ankle joints. Based on previous studies of biological joint impedance and the mechanics of able-bodied gait, an impedance-based controller has been developed for a powered knee and ankle prosthesis that integrates knee swing initiation and powered plantar flexion in late stance with increasing...
In this paper we present a series of design directions for the development of affordable, compliant, modular, underactuated robot fingers, that can be used as prostheses by amputees that suffer from various partial hand amputations (index to pinky fingers are considered). Our design is based on parametric models that have been derived from hand anthropometry studies. Various interfaces have been considered...
Improving the intuitiveness of the interaction between human and machine is an important issue for powered lower-limb prosthesis control. In this research, we aimed to evaluate the potential of using surface electromyography (EMG) signals measured from transtibial amputees' residual muscles to directly control the position of prosthetic ankle. In this research, one transtibial amputee subject and...
In electromyography pattern-recognition-based control of a multifunctional prosthesis, it would be inevitable for the users to unintentionally perform some classes of movements that are excluded from the training motion classes of a classifier, which might decay the performance of a trained classifier. It remains unknown how these untrained movements, designated as non-target movements (NTMs) in the...
In this study, we used a simulation of upcoming low-resolution visual neuroprostheses to evaluate the benefit of embedded computer vision techniques in a wayfinding task. We showed that augmenting the classical phosphene rendering with the basic structure of the environment — displaying the ground plane with a different level of brightness — increased both wayfinding performance and cognitive mapping...
Brain computer interface (BCI) control predominately uses visual feedback. Real arm movements, however, are controlled under a diversity of feedback mechanisms. The lack of additional BCI feedback modalities forces users to maintain visual contact while performing tasks. Such stringent requirements result in poor BCI control during tasks that inherently lack visual feedback, such as grasping, or when...
Millions of people worldwide face partial or total vision loss due to inherited photoreceptor degenerative diseases, which currently have no cure. Retinal prostheses have been developed to restore vision by electrically stimulating surviving retinal neurons, but have low spatial resolution and nonselectively stimulate retinal ganglion cell (RGC) axons along with somata. We propose a biomimetic solution:...
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