GeroScience is a bi-monthly, international, peer-reviewed journal that publishes articles related to research in the biology of aging and research on biomedical applications that impact aging. The scope of articles to be considered include evolutionary biology, biophysics, genetics, genomics, proteomics, molecular biology, cell biology, biochemistry, endocrinology, immunology, physiology, pharmacology, neuroscience, and psychology. Articles concerning clinical studies may also be considered but the results should reveal underlying biological mechanisms of aging. Studies must reflect more than issues related to the care and treatment of geriatric patients. Papers concerned with social, economic, and political issues of aging will generally not be considered unless they relate directly to biomedical gerontology. In addition to manuscripts emerging from original research, the journal actively solicits research reviews of important topics in biomedical gerontology. Other types of manuscripts are also acceptable, such as commentaries, debates, and meeting reports. This is the official journal of the American Aging Association: http://www.americanagingassociation.org/
AGE
Description
Identifiers
ISSN | 0161-9152 |
e-ISSN | 1574-4647 |
DOI | 10.1007/11357.1574-4647 |
Publisher
Springer International Publishing
Additional information
Data set: Springer
Articles
Cognitive functions are dependent upon intercommunications between the cellular components of the neurovascular unit (NVU). Vascular risk factors are associated with a more rapid rate of cognitive decline with aging and cerebrovascular diseases magnify both the incidence and the rate of cognitive decline. The causal relationship between vascular risk factors and injury to the NVU is, however, lacking...
Reviews on cardiovascular fitness and cognition in older adults suggest that a higher level of cardiorespiratory fitness may protect the brain against the effects of aging. Although studies reveal positive effects of cardiorespiratory fitness on executive function, more research is needed to clarify the underlying mechanisms of these effects in older adults. The aim of the current study was to assess...
Aging and stroke alter the composition of the basement membrane and reduce the perivascular distribution of cerebrospinal fluid and solutes, which may contribute to poor functional recovery in elderly patients. Following stroke, TGF-β induces astrocyte activation and subsequent glial scar development. This is dysregulated with aging and could lead to chronic, detrimental changes within the basement...