Patients often mention the return of the cancer and express their anxiety about a possible invasion of their body by the cancer or the spread of the disease in other organs. Particularly, post-treatment, they describe the fear of cancer recurrence (FCR) as a sword of Damocles hanging over their head and threatening their future peace by spreading the notion of uncertainty. Some authors refer to the FCR as a central dimension in many patients, and others point out the problem of pervasive fear of return and/or progression of the disease being one of the most often reported difficulties by cancer survivors. The objective of our work is to present a literature review and propose terms of psychological interventions focused on FCR.