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Background and aims
Ibogaine is an indole alkaloid used in rituals of the African Bwiti tribe. It is also used in non‐medical settings to treat addiction. However, ibogaine has been linked to several deaths, mainly due to cardiac events called torsades des pointes preceded by QTc prolongation as well as other safety concerns. This study aimed to evaluate the cardiac, cerebellar and psychomimetic...
Background and Aims
In 2017, the US Food and Drug Administration (FDA) proposed to reduce nicotine in cigarettes to minimally or non‐addictive levels. This study qualitatively explored perceptions of nicotine and addiction, both independently and in response to messages communicating about nicotine reduction.
Design
Qualitative study using focus groups. Participants described their perceptions...
Background and aims
Non‐invasive brain stimulation has shown potential in clinical applications aiming at reducing craving and consumption levels in individuals with drug addiction or overeating behaviour. However, it is unclear whether these intervention effects are maintained over time. This study aimed to measure the immediate, short‐ and long‐term effects of excitatory transcranial direct current...
Background and aims
Variation in the TAS2R38 taste receptor gene alters the ability to taste bitter compounds. We tested whether TAS2R38 variation influences early smoking behaviours in adolescence, a critical period of acquisition when taste may influence the natural course of tobacco use.
Design and participants
Observational study (Nicotine Dependence in Teens [NDIT]). Cox proportional hazards...
Background/Aims
The COVID‐19 pandemic has significantly impacted face‐to‐face research. This has propelled ideas and plans for more remote styles of research and provided new perspectives on conducting research. This paper aimed to identify challenges specific to conducting remote forms of experimental addiction research, although some of these challenges apply to all types of addiction research...
Background and Aims
Individuals impacted by someone else’s alcohol, illicit drug, gambling and gaming problems (affected others) experience extensive harms. To our knowledge, this is the first systematic review and meta‐analysis to determine the effectiveness of psychosocial interventions delivered to affected others across addictions.
Methods
This review adhered to the Preferred Reporting Items...
Background and Aims
Non‐invasive brain stimulation (NIBS) methods have showed promising results for the treatment of tobacco use disorder, but little is known about the efficacy of NIBS on sustained tobacco abstinence. We aimed to assess its effectiveness for long‐term smoking cessation.
Methods
Systematic review and meta‐analysis of randomized controlled trials (RCT). PubMed, Cochrane library,...
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