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Aims
To assess whether naloxone prescribing in clinical contexts targeted pain patients most at risk for opioid overdose.
Design
A retrospective cohort study using data from the Health Facts Database.
Setting
Over 600 United States healthcare facilities.
Participants
Three patient groups were followed for 2 years during 2009 to 2017: individuals with shoulder or long bone fractures (n = 252...
Background and aims
Whether expanded access to naloxone reduces perceptions of risk about opioid use has been subject to debate. Our aim was to assess how implementation of naloxone access laws shapes perceived risk of heroin use.
Design
Using data from the restricted‐access National Survey on Drug Use and Health, Prescription Drug Abuse Policy System and the US Census, we applied two‐way fixed‐effects...
Background and aims
Although most opioid‐related mortality in Australia involves prescription opioids, most research to understand the impact of naloxone supply on opioid‐related mortality has focused upon people who inject heroin. We aimed to examine the cost and probable impact of up‐scaling naloxone supply to people who are prescribed opioids.
Design
Decision‐tree model. Four scenarios were...
Background and aims
Opioid‐related overdose death rates continue to rise in the United States, especially in racial/ethnic minority communities. Our objective was to determine if US municipalities with high percentages of non‐white residents have equitable access to the overdose antidote naloxone distributed by community‐based organizations.
Methods
We used community‐based naloxone data from the...
Aims
To measure and evaluate clinical response to nasal naloxone in opioid overdoses in the pre‐hospital environment.
Design
Randomised, controlled, double‐dummy, blinded, non‐inferiority trial, and conducted at two centres.
Setting
Participants were included by ambulance staff in Oslo and Trondheim, Norway, and treated at the place where the overdose occurred.
Participants
Men and women age...
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