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Arterial pulse waveforms contain a wealth of information about the cardiovascular system. There is a lack of physical meaning in the mathematical model of arterial pulse waves, while the physical model fails to offer individuality as too many assumptions are involved. In this article, we focus on promoting the interpretability of the arterial pulse mathematical model. The proposed method is based...
This study examines the use of computer‐aided analysis to evaluate the biomechanical performance of Schanz screws made from different additive manufacturing materials (Ti6Al4V, 316 L, Inconel 625, and Inconel 718) in a pertrochanteric fixator for the treatment of intertrochanteric femoral fractures. Intertrochanteric fractures (ITFs) are severe traumas often seen in the elderly population and can...
Low back pain has been reported to have a high prevalence among occupational drivers. Whole‐body vibration during the driving environment has been found to be a possible factor leading to low back pain. Vibration loads might lead to degeneration and herniation of the intervertebral disc, which would increase incidence of low back problems among drivers. Some previous studies have reported the effects...
The inflammatory phase is an important event in the skin wound healing process. The deposition of granulation tissue in the wound bed and the rebuilding of the vascular network occur as inflammation diminishes. An angiogenic component in the formation of granulation tissue is the secretion of vascular endothelial growth factor, which assists in the chemotaxis, proliferation, and replication of fibroblasts...
In this paper, we develop an algorithm to simulate blood flows in aneurysmal arteries and focus on the construction of robust and efficient multilevel preconditioners to speed up the convergence of both linear and nonlinear solvers. The work is motivated by the observation that in the local aneurysmal region, the flow is often quite complicated with one or more vortices, but in the healthy section...
Restenosis typically occurs in regions of low and oscillating wall shear stress, which also favor the accumulation of atherogenic macromolecules such as low‐density lipoprotein (LDL). This study aims to evaluate LDL transport and accumulation at the carotid artery bifurcation following carotid artery stenting (CAS) by means of computational simulation. The computational model consists of coupled blood...
Vertex models have been extensively used for simulating the evolution of multicellular systems, and have given rise to important global properties concerning their macroscopic rheology or jamming transitions. These models are based on the definition of an energy functional, which fully determines the cellular response and conclusions. While two‐dimensional vertex models have been widely employed,...
A major challenge in the computational fluid dynamics modeling of the heart function is the simulation of isovolumetric phases when the hemodynamics problem is driven by a prescribed boundary displacement. During such phases, both atrioventricular and semilunar valves are closed: consequently, the ventricular pressure may not be uniquely defined, and spurious oscillations may arise in numerical simulations...
Acupuncture points have a positive effect on the auxiliary prevention and treatment of diseases, so medical devices such as acupuncture robots often need to combine acupuncture points to improve the treatment effect when working, however, intelligent acupoint selection technology is not yet mature, the automatic rapid and accurate positioning of acupoints is still challenging. Therefore, this paper...
We present a numerical investigation of the photothermal response of gold nanoshell (AuNS) dimers when subjected to femtosecond laser pulse irradiation. The time‐varying temperature fields for core–shell AuNS dimers are quantified by implementing finite element modeling, integrating the electromagnetic and thermal dual‐physics simulations. Given the ultrafast nature of laser pulses, we employ a two‐temperature...
Recent publications report that although the mitochondria population in an axon can be quickly replaced by a combination of retrograde and anterograde axonal transport (often within less than 24 hours), the axon contains much older mitochondria. This suggests that not all mitochondria that reach the soma are degraded and that some are recirculating back into the axon. To explain this, we developed...
This study focuses on evaluating the response of the Total Human Model for Safety™ lower extremity finite element model under blast loading. Biofidelity of the lower extremity model was evaluated against experiments with impact loading equivalent to underbody blast. The model response was found to match well with the experimental data for the average impactor speeds of 7 and 9.3 m/s resulting in an...
Professional medical experts use a visual electroencephalography (EEG) signal for epileptic seizure detection, although this method is time‐consuming and highly subject to bias. The majority of previous epileptic detection techniques have poor efficiency, detection performance and also which are unsuited to handle large datasets. In order to solve the aforementioned issues and to assist medical professionals...
Optimal control musculoskeletal simulation is a valuable approach for studying fundamental and clinical aspects of human movement. However, the high computational demand has long presented a substantial challenge, creating a need to improve simulation performance. The OpenSim Moco software package permits musculoskeletal simulation problems to be solved in parallel on multicore processors using the...
In this study, we investigated the impact of various simulated skull bone geometries on the determination of skull speed of sound and acoustic attenuation values via optimization using transmitted pressure amplitudes beyond the bone. Using the hybrid angular spectrum method (HAS), we simulated ultrasound transmission through four model sets of different geometries involving sandwiched layers of diploë...
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