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The analysis of whole‐genome sequence (WGS) data using longitudinal phenotypes offers a potentially rich resource for the examination of the genetic variants and their covariates that affect complex phenotypes over time. We summarize eight contributions to the Genetic Analysis Workshop 18, which applied a diverse array of statistical genetic methods to analyze WGS data in combination with data from...
Genome‐wide association studies have led to the discovery of thousands of susceptibility genetic variants (typically single‐nucleotide polymorphisms [SNPs]) for a wide range of complex diseases and traits commonly measured at a single point in time. Although many novel genotype‐phenotype associations have been identified and successfully replicated using cross‐sectionally measured phenotypes, there...
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