The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Objective
The current analysis used functional magnetic resonance imaging (fMRI) to explore a model of energy regulation postulating that the hippocampus integrates interoceptive signals and environmental stimuli to suppress responding to food cues. It was hypothesized that hippocampal activity would increase in response to food cues under postnutritive relative to fasted conditions, given the role...
Objective
The Awareness, Care, and Treatment in Obesity Management–International Observation (ACTION‐IO) study (ClinicalTrials.gov identifier NCT03584191) aimed to identify perceptions, attitudes, behaviors, and barriers to effective obesity care in people with obesity (PwO) and health care professionals (HCPs). This study presents the results from Mexico.
Methods
An online survey was conducted...
Objective
Obesity is a major public health challenge, and the US military veteran population is disproportionately affected. Using deidentified records from a local weight management clinic and a national clinical data repository, obesity pharmacotherapy use and effectiveness for weight loss and obesity comorbidities in this vulnerable population were assessed.
Methods
During the initial year of...
Objective
Altered hormonal regulation, including cortisol, is a proposed mechanism linking adiposity to obesity‐related disorders. We examined the association of anthropometric, adipokine, and body fat distribution measures of adiposity with morning serum cortisol in an African American (AA) cohort.
Methods
We investigated the cross‐sectional associations of adiposity measures (BMI, waist circumference,...
Objective
This study aimed to compare the effects of two aerobic exercise programs of different intensities on energy expenditure.
Methods
This was a single‐center randomized controlled trial of patients with severe obesity allocated to a 24‐week moderate‐intensity continuous training (MICT) program or a combined MICT with high‐intensity interval training (HIIT/MICT) program. The primary outcome...
Objective
This study compares children with severe obesity and children with mild obesity/overweight participating in family‐based obesity treatment (FBT) on change in (1) relative weight and adiposity and (2) psychosocial distress.
Methods
Children 7 to 11 years old (N = 241) and their parents participated in 12 months of behavioral treatment (FBT + maintenance treatment) and completed anthropometric,...
Objective
The purpose of this study was to investigate the associations of urinary phthalates and bisphenols at age 6 years old with body fat and cardiovascular risk factors at 6 and 10 years and with the change from 6 to 10 years.
Methods
Among 471 Dutch children, the phthalates and bisphenols urinary concentrations at 6 years and BMI, fat mass index, android fat mass, blood pressure, glucose,...
Objective
This study aimed to uncover genetic contributors to adiposity in early life.
Methods
A genome‐wide association study of childhood body fatness in 34,401 individuals within the Nurses’ Health Studies and the Health Professionals Follow‐up Study was conducted. Data were imputed to the 1000 Genomes Phase 3 version 5 reference panel.
Results
A total of 1,354 single‐nucleotide polymorphisms...
Objective
The purpose of this study was to examine associations between self‐reported weight history and sarcopenic obesity in adults with advanced knee osteoarthritis (OA).
Methods
Self‐reported weight history was collected from n = 151 adults (58.9% female) with knee OA and BMI ≥30 kg/m2 in a cross‐sectional study. Body composition was assessed using dual‐energy x‐ray absorptiometry. Sarcopenic...
Objective
Models such as family‐based treatment (FBT), delivered to both the parent and child, are considered the most efficacious intervention for children with obesity. However, recent research suggests that parent‐based treatment (PBT; or parent‐only treatment) is noninferior to FBT. The aim of this study was to evaluate the comparative costs of the FBT and PBT models.
Methods
A total of 150...
Objective
This study aimed to investigate the shortcoming of BMI as a measurement of adiposity in patients with familial partial lipodystrophy (FPLD).
Methods
Two different matching procedures were used to compare 55 FPLD versus control patients with severe obesity (N = 548 patients) to study the relationship between body weight, fat distribution, and metabolic diseases, such as diabetes mellitus,...
Objective
The purpose of this study was to investigate the peripheral concentrations of leptin and neuropeptides taking part in the melanocortin pathway in hypothalamic obesity (HO) associated with craniopharyngioma (CP) and to find a peripheral marker for diagnosis.
Methods
Thirty‐one patients (52% girls; median age 16 years) with CP were enrolled in the study group. They were grouped as CP with...
Objective
The aryl hydrocarbon receptor (AHR) plays a key role in obesity. In vitro studies revealed that the tryptophan metabolite kynurenine (Kyn) activates AHR signaling in cultured hepatocytes. The objective of this study was to determine whether Kyn activated the AHR in mice to induce obesity.
Methods
Mice were fed a low‐fat diet and the same diet supplemented with Kyn. Body mass, liver status,...
Objective
The aim of this study was to identify longitudinal trajectories of conjoint development of executive function (EF) and obesity among a diverse sample of poor, rural youth and to evaluate individual differences in infant growth, parental BMI, and cumulative risk.
Methods
Participants included 948 youth from the Family Life Project. Child anthropometrics were measured at 2 and 6 months...
Objective
Adipose tissue macrophages (ATMs) play critical roles in obesity‐associated inflammation that contributes to metabolic dysfunction. Talabostat (TB) exerts some therapeutic effects on tumors and obesity. However, it remains unknown whether the metabolic benefits of TB on obesity is dependent on ATM‐mediated adipose inflammation.
Methods
Male C57BL/6J mice were fed a normal chow diet (NCD)...
Obesity is a chronic, multifactorial disease associated with a large number of comorbidities. The clinical management of obesity involves a stepwise integrated approach, beginning with behavioral and lifestyle modification, followed by antiobesity medications, endobariatric procedures, and bariatric surgery. Weight gain and subsequent obesity are common side effects of medications, such as prednisone...
Objective
This study aimed to investigate the role of cytokines as intermediates in the pathway from increased adiposity to disease.
Methods
BMI and circulating levels of up to 41 cytokines were measured in individuals from three Finnish cohort studies (n = 8,293). Mendelian randomization (MR) was used to assess the impact of BMI on circulating cytokines and the impact of BMI‐driven cytokines on...
Objective
The study’s aim was to determine to what extent total visceral adipose tissue (VAT) volume (VVAT‐T) measured from segmented VAT areas (AVAT) on all axial computed tomography (CT) sections (thickness of 5 mm) between the diaphragm and pelvic floor can be predicted by the AVAT of commonly selected landmark sections in patients with overweight or obesity.
Methods
A total of 113 patients...
Objective
Stay‐at‐home orders in response to the coronavirus disease 2019 (COVID‐19) pandemic have forced abrupt changes to daily routines. This study assessed lifestyle changes across different BMI classifications in response to the global pandemic.
Methods
The online survey targeting adults was distributed in April 2020 and collected information on dietary behaviors, physical activity, and mental...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.