The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Objective
Early life is a critical window for adiposity programming. This study investigated whether fat mass percentage (FM%), fat mass index (FMI), abdominal fat, and fat‐free mass (FFM) in early life track into childhood and whether there are sex differences and differences between infant feeding types.
Methods
Detailed body composition was longitudinally measured by air‐displacement plethysmography,...
Objective
This study investigated, in a large pediatric population, whether magnetic resonance imaging (MRI) evidence of mediobasal hypothalamic (MBH) gliosis is associated with baseline or change over 1 year in body adiposity.
Methods
Cross‐sectional and prospective cohort analyses were conducted within the Adolescent Brain Cognitive Development Study. Study 1 included 169 children with usable...
Objective
Across the world, it remains legal to discriminate against people because of their weight. Although US studies demonstrate public support for laws to prohibit weight discrimination, multinational research is scarce. The present study conducted a multinational comparison of support for legislative measures to address weight discrimination and bullying across six countries.
Methods
Participants...
Objective
This study examined the relationship between parental obesity polygenic risk and children’s BMI throughout adolescence. Additionally, from a smaller subsample, the objective was to assess whether parental polygenic risk score (PRS) may act as a proxy for offspring PRS in studies lacking offspring genetic data.
Methods
A total of 8,561 parent‐offspring (age 13‐19 years) trios from the...
Objective
Maternal obesity increases the risks for adverse pregnancy and offspring outcomes but with large heterogeneity. This study examined changes to the maternal metabolic milieu across pregnancy in women with obesity. It identified differences between a metabolically unhealthy obesity (MUO) phenotype and a metabolically healthy obesity (MHO) phenotype, as well as the differences in offspring...
Objective
The Chinese government decisively imposed nationwide confinement in response to the COVID‐19 outbreak. This study aimed to evaluate the impact of the COVID‐19 pandemic on the progression of obesity in children and adolescents in Changshu, China.
Methods
Based on the Health Promotion Program for Children and Adolescents (HPPCA), which is a prospective cross‐sectional and school‐based study,...
Objective
The aim of this study was to investigate whether digitally re‐posing three‐dimensional optical (3DO) whole‐body scans to a standardized pose would improve body composition accuracy and precision regardless of the initial pose.
Methods
Healthy adults (n = 540), stratified by sex, BMI, and age, completed whole‐body 3DO and dual‐energy X‐ray absorptiometry (DXA) scans in the Shape Up! Adults...
Objective
Obesity is becoming a global public health problem, but it is unclear how it impacts different generations over the life course. Here, a descriptive analysis of the age‐related changes in anthropometric measures and related cardiometabolic risk factors across different generations was performed.
Methods
The development of anthropometric measures and related cardiometabolic risk factors...
A sufficient and balanced maternal diet is critical to meet the nutritional demands of the developing fetus and to facilitate deposition of fat reserves for lactation. Multiple adaptations occur to meet these energy requirements, including reductions in energy expenditure and increases in maternal food intake. The central nervous system plays a vital role in the regulation of food intake and energy...
Dysregulation of hepatic glucose production (HGP) and glucose disposal leads to hyperglycemia and type 2 diabetes. Hyperglycemia results from the declining ability of insulin to reduce HGP and increase glucose disposal, as well as inadequate ß‐cell compensation for insulin resistance. Hyperglucagonemia resulting from reduced suppression of glucagon secretion by insulin contributes to hyperglycemia...
Objective
Beyond sleep duration, other facets of sleep such as variability and timing may be associated with obesity risk in youth. However, data are limited. Using a longitudinal design, this study tested whether multiple facets of sleep were associated with fat mass gain over 1 year.
Methods
A convenience sample of non‐treatment‐seeking youth (age 8‐17 years) wore actigraphy monitors for 14 days...
Objective
This study examined the associations of central adiposity gain from midchildhood to early adolescence with cardiometabolic health markers in early adolescence.
Methods
A total of 620 participants were studied in Project Viva. In midchildhood (mean age = 7.8 years) and early adolescence (12.9 years), waist circumference and dual‐energy x‐ray absorptiometry‐measured visceral adipose tissue,...
Objective
Excess dietary fat and sodium (NaCl) are both associated with obesity and metabolic dysfunction. In mice, high NaCl has been shown to block high‐fat (HF) diet–induced weight gain. Here, the impact of an HF/NaCl diet on metabolic function in the absence of obesity was investigated.
Methods
Wild‐type mice were administered chow, NaCl (4%), HF, and HF/NaCl diets. Metabolic analysis was performed...
Objective
Overweight, defined as excessive fat mass, is a long‐standing worldwide public health challenge. Traditional anthropometric measures used to identify overweight and obesity do not assess body composition. The aim of this study was to examine population trends in general and abdominal fat mass during the past two decades.
Methods
This study included participants from one or more consecutive...
Objective
Orexin/hypocretin (Ox) and its receptors (OxR), a neuroendocrine system centrally regulating sleep/wakefulness, were implicated in the regulation of peripheral metabolism. It was hypothesized that human adipose tissue constitutes a direct target of the OxA/OxR system that associates with distinct metabolic profile(s).
Methods
Serum Ox levels and abdominal subcutaneous and visceral adipose...
Objective
Increased carotid intima‐media thickness (cIMT) is associated with cardiovascular (CV) events in adults and with elevated CV risk factors in youth. The aim of this study was to determine whether obesity has an direct or indirect association with cIMT.
Methods
Structural equation modeling was used to elucidate pathways for obesity to change cIMT. Complete data were collected twice on 294...
Objective
The aim of this study was to examine the effectiveness of a school‐based gamification strategy to prevent childhood obesity.
Methods
Schools were randomized in Santiago, Chile, between March and May 2018 to control or to receive a nutrition and physical activity intervention using a gamification strategy (i.e., the use of points, levels, and rewards) to achieve healthy challenges. The...
Objective
Health system data were assessed for how well they can estimate obesity prevalence in census tracts.
Methods
Clinical visit data were available from two large health systems (Kaiser Permanente Washington and University of Washington Medicine) in King County, Washington, as were census tract–level obesity prevalence estimates from the Behavioral Risk Factor Surveillance System (BRFSS)...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.