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Objective
This meta‐analysis aimed to assess the effect of mobile application (app) interventions on weight loss in patients with type 2 diabetes.
Methods
Electronic databases were searched for randomized controlled trials examining the use of mobile app interventions with outcomes on weight loss evaluated by body weight or other measures such as BMI or waist circumference. A random‐effects model...
Objective
This study investigated which antenatal and postnatal factors determine offspring adiposity during the first 2 years of life.
Methods
Participants were mother and child pairs (N = 224). Offspring percent fat mass (%FM) was obtained using quantitative nuclear magnetic resonance at 11 time points between ages 0.5 and 24 months. Independent variables included race, age, gestational weight...
Objective
Phosphorylated fetuin‐A (pFet‐A) inhibits insulin action and has been shown to be associated with obesity and insulin resistance. The objective of this cohort study was to assess the effect of incremental body weight loss on alterations in serum pFet‐A and indexes of insulin sensitivity.
Methods
A total of 16 men with obesity attained a targeted weight loss of 8% to 10% of their initial...
Objective
This study aimed to characterize young adults who experienced significant weight gains (> 10%) over 3 years in a weight gain prevention program.
Methods
Secondary data analysis from the Study of Novel Approaches to Weight Gain Prevention (SNAP), a randomized trial comparing two self‐regulation interventions and a control arm in young adults (18‐35 years; BMI 21‐30.9 kg/m2), was used...
Objective
This study investigated whether the levels of specific serum microRNAs (miRNAs) were altered following diet‐induced weight loss and whether the serum miRNAs differed in the presence of the metabolic syndrome.
Methods
The study was a weight loss intervention trial with a prescribed energy deficit of approximately 500 kcal/d. Levels of 22 miRNAs were determined in serum samples from 85...
Objective
This study investigated associations between stress (general stress, parenting distress, and household chaos) and adiposity among parents of young children.
Methods
The sample consisted of 49 mothers and 61 fathers from 70 families with young children living in Ontario, Canada. Linear regression using generalized estimating equations was used to investigate associations between stress...
Objective
This study examined the dose‐response relationship between changes in physical activity (PA) and subsequent incidence or remission of overall and abdominal obesity.
Methods
A total of 113,950 healthy individuals aged ≥ 18 years participating in the Taiwan MJ Cohort were included. Two‐year changes in PA between the first and second examination were linked to subsequent development and...
Objective
The aims of this study are to examine the potential association between grandmaternal BMI and grandchild’s birth weight (BW) and whether maternal BW and BMI mediate this association.
Methods
Data of 209 grandmother‐mother pairs and 355 grandchildren from the Isle of Wight birth cohort in the UK were analyzed using path analysis.
Results
An indirect effect of grandmaternal BMI on increasing...
Objective
This study aimed to investigate whether antibiotic exposure during pregnancy and infancy was associated with childhood overweight or obesity.
Methods
PubMed, Embase, and Cochrane Library databases were searched from the inception date to April 18, 2019, to identify observational studies that investigated the association between antibiotic exposure during pregnancy and infancy and childhood...
Objective
This study determined whether striatal dopamine (DA) release is affected by food ingestion and whether the DA response to high‐calorie food images is greater in the fasted than in the fed state in people with obesity.
Methods
Striatal DA release was evaluated in 10 people with obesity and prediabetes after consuming a meal to satiation and after fasting overnight as well as in response...
Objective
This study investigated the effect of 3 weeks of high‐sugar (“Sweet”) versus low‐sugar (“Plain”) breakfast on energy balance, metabolic health, and appetite.
Methods
A total of 29 healthy adults (22 women) completed this randomized crossover study. Participants had pre‐ and postintervention appetite, health, and body mass outcomes measured, and they recorded diet, appetite (visual analogue...
Objective
With the discovery of thermogenic adipocytes in humans, it has been hypothesized that enhancing adaptive thermogenesis may improve obesity. Although many studies have found that ginseng can improve obesity, the beneficial effects of ginsenoside Rd on obesity and its mechanisms have not been studied.
Methods
High‐fat diet‐induced obese mice were used as the study subjects, with intraperitoneal...
Objective
This study aimed to identify obesity trajectories from childhood to adolescence (2‐15 years of age) and investigate differences in behavioral, eating, and adrenocortical regulation by trajectory membership.
Methods
A total of 1,077 households from the National Institute of Child Health and Human Development Study of Early Child Care and Youth Development were included. Anthropometrics...
Objective
Inactivity and inflammation are linked to obesity and insulin resistance. It was hypothesized that MyD88 (mediates inflammation) knockout from muscle (MusMyD88−/−) would prevent, whereas miR146a−/− (MyD88 inhibitor) would exacerbate, inactivity‐induced metabolic disturbances.
Methods
Cre‐control, MusMyD88−/−, and miR146a−/− mice were given running wheels for 5 weeks to model an active...
Objective
The aim of this study was to investigate whether the level, rate, and acceleration of BMI growth differ according to the presence or absence of adult cardiometabolic (CM) risks.
Methods
BMI was measured in 1,000 Chileans at nine time points from birth to 23 years, and metabolic syndrome and its components were assessed at young adulthood. BMI growth was analyzed in the following three...
Objective
This study aimed to 1) analyze the criterion validity of the Slaughter equations (Slg‐Eq) and bioelectrical impedance analysis (BIA) to estimate body fat percentage (BFP) and fat mass index (FMI) at different degrees of obesity in children compared with dual‐energy x‐ray absorptiometry (DXA) and 2) determine their agreement over time.
Methods
Ninety‐two children with overweight or obesity...
Objective
This study aimed to evaluate ertugliflozin in patients with overweight and obesity with type 2 diabetes mellitus.
Methods
Data from three placebo‐controlled, randomized, Phase 3 studies were pooled. Patients with baseline BMI ≥ 25 (1,377/1,544; 89%) were assessed with a stratification by BMI subgroup.
Results
At week 26, reductions from baseline in glycated hemoglobin A1c (HbA1c), fasting...
Objective
This study aimed to evaluate the presence of the overvaluation of shape and weight and its associated features in patients with obesity but no eating disorder who were seeking treatment from a specialist unit.
Methods
Overall, 1,134 patients with obesity but no Diagnostic and Statistical Manual of Mental Disorders eating disorder diagnosis were included. The Eating Disorder Examination...
Objective
The aim of this study was to test the protein leverage hypothesis in a cohort of youth with obesity.
Methods
A retrospective study was conducted in a cohort of youth with obesity attending a tertiary weight management service. Validated food questionnaires revealed total energy intake (TEI) and percentage of energy intake from carbohydrates (%EC), fats (%EF), and proteins (%EP). Individuals...
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