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This study presents combination of advantages in MEMS technology and molecular methods for detection of methicillin resistant gene, mecA, in Staphylococcus aureus. A disposable MEMS DNA biosensor was designed and fabricated for optical and electrochemical detections. Adsorption of DNA on gold electrode was examined theoretically and experimentally. In theoretical studies, Lennard Jones potential energies...
A label-free biosensor based on localized surface plasmon resonance (LSPR) was developed. A multi-channel microfluidic chip was integrated with the sensor, providing referencing channel to minimize noise level and improving the throughput. With a CCD as a detector, a sensitivity of 10-4 RIU was demonstrated. The adsorption of S-layer protein was detected successfully by the sensor system.
This paper reports the implementation and calibration of a microscopic three-electrode electrochemical sensor integrated with a polydimethylsiloxane (PDMS) microchannel to form a rapid prototype chip technology that is used to develop sensing modules for biomolecular signals. The microfluidic/microelectronic fabrication process yields identical, highly uniform, and geometrically well-defined microelectrodes...
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