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This study aimed to evaluate the host genetic liability of coronavirus disease 2019 (covid‐19) with platelet traits using the Mendelian randomization (MR) approach. We conducted a bidirectional two‐sample MR using summary statistics from the largest genome‐wide association study of three variables, covid‐19 severity (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2] infection, covid‐19...
Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in developed countries. It is a disease of the elderly, usually incurable and characterized by significant clinical and biological heterogeneity. Many patients are diagnosed after the incidental finding of a sustained lymphocytosis, while others present with symptomatic disease requiring treatment. Clinical features arise from immune...
Chronic lymphocytic leukaemia (CLL) is the commonest leukaemia in the Western world. It is a disease of the elderly and is usually incurable except in a minority of patients suitable for allogeneic haematopoietic stem cell transplantation. Many CLL patients are asymptomatic and the condition is diagnosed following the incidental finding of a sustained lymphocytosis. Clinical features arise as a result...
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