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Supersonic Shear Imaging (SSI) is a quantitative stiffness imaging technique based on the combination of a radiation force induced in tissue by an ultrasonic beam and ultrafast ultrasound imaging sequence (up to more than 10000 frames per second) catching in real time the propagation of the resulting shear waves. Local shear wave speed is estimated and enables the two dimensional mapping of shear...
This papers reports on methodologies and outcome of a study aiming at developing robust tool to evaluate and classify histology images of cervical cancer. Using the histology images acquired from the pathology laboratories in an Indonesian hospital, this study aims to classify cervical biopsy images based on four well known discriminatory features a) the ratio of nuclei to cytoplasm b) diameter of...
The effectiveness of an imaging technique is often based on the ability to image quantitatively both morphological and physiological functions of the tissue. Here we present several ultrasound-based imaging techniques capable of visualizing both structural and functional properties of living tissue. Each imaging system utilizes custom-made, targeted nanoparticles developed to probe specific molecular...
Coherent backscattering (CBS) is a photon weak-localization phenomenon that gives rise to an enhanced backscattering of light by random media. This effect has been previously investigated using coherent light sources. Here we show that CBS can be observed using broadband low-coherence light. We demonstrate, for the first time to the best of our knowledge, that low-coherence detection substantially...
Prostate cancer is the highest-incidence and second leading cancer killer of men in the US. Its diagnosis now relies virtually exclusively on biopsy, and many surgical procedures are performed inappropriately because of the unknown prior spread of cancer. Ultrasonic spectrum analysis of radio-frequency echo signals may offer a means of reducing unnecessary biopsies and surgery, and improving biopsy...
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