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Supersonic Shear Imaging (SSI) is a quantitative stiffness imaging technique based on the combination of a radiation force induced in tissue by an ultrasonic beam and ultrafast ultrasound imaging sequence (up to more than 10000 frames per second) catching in real time the propagation of the resulting shear waves. Local shear wave speed is estimated and enables the two dimensional mapping of shear...
The effectiveness of an imaging technique is often based on the ability to image quantitatively both morphological and physiological functions of the tissue. Here we present several ultrasound-based imaging techniques capable of visualizing both structural and functional properties of living tissue. Each imaging system utilizes custom-made, targeted nanoparticles developed to probe specific molecular...
It is important of diagnosing not only primary tumors but also metastases accurately. Recently, we have established murine lymph node metastasis model and developed a new method to reconstruct the two- and three-dimensional (2D/3D) vessel structures in the model by using nanobubbles (NBs) and high-frequency ultrasound imaging system. In the present study, we investigated the characteristics of 2D/3D...
Prostate cancer is the highest-incidence and second leading cancer killer of men in the US. Its diagnosis now relies virtually exclusively on biopsy, and many surgical procedures are performed inappropriately because of the unknown prior spread of cancer. Ultrasonic spectrum analysis of radio-frequency echo signals may offer a means of reducing unnecessary biopsies and surgery, and improving biopsy...
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