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Thermal ablation has been investigated as a treatment for a variety of cancers. Heat treatments have not gained large-scale clinical acceptance due to inconsistencies in controlling heat deposition in vivo and the lack of precise temperature measurement. Interstitial ultrasound provide a good method of controlling the radial depth of a thermal lesion and the applicator designs evaluated in this study...
Magnetic resonance elastography (MRE) is a method that can visualize the propagating acoustic strain waves in elastic materials under mechanical excitation. The local quantitative values of shear modulus are derived from the acquired data. The MRE could improve early detection of pathology because it is known that malignant tumors tend to be much harder than normal tissues and most benign tumors....
Positron emission tomography (PET) is complimentary to other imaging modalities such as CT and MRI and provides a unique and effective means for detecting tumors in vivo through tissue metabolism measurement. At the majority of clinics, only the attenuation-corrected images are read by the physician for tumor diagnosis; the unconnected images are not examined, losing critically important information...
According to neuro-endocrine-immune theory, we have done research and tried to find possible explanations of the relationship of trilogy imaging characteristics of thermal texture mapping (TTM) and patients with the malignancies, or the patients susceptible to malignancies. We performed another two experiments to study mechanism of trilogy imaging characteristics, however, the result was not as expected...
The purpose of this research is to classify the pattern on the surface of the nevus. The digital image that contains one nevus is classified into three kinds of patterns of homogeneous pattern, globular pattern, and reticular pattern by the texture analysis. The tumor part in the image is specified first, and the specified tumor part is divided into some sub-images. Afterwards, the amount of the texture...
Solid tumors and other pathologies can be treated using laser thermal ablation under interventional magnetic resonance imaging (iMRI) guidance. We developed a model to predict cell death from MR thermometry measurements and applied it to in vivo rabbit brain data. To align post-ablation T2-weighted spin-echo MR lesion images to gradient echo MR images, from which temperature is derived, we used a...
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