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Irreversible electroporation (IRE) uses high-voltage pulses applied to tissue, which cause dielectric breakdown of cell membranes resulting in cell death. IRE is a promising technique for ablation of nonresectable tumors because it can be configured to spare critical structures such as blood vessels. A consequence of pulse application is an increase in tissue electrical conductivity due to current...
Electrical Impedance Tomography (EIT) measurements normally use a VCCS (Voltage Controlled Current Source) to excite the object/media to be studied. In general a multiplexer array is used for selecting the excitation and measurement electrodes which limits the maximum current excitation frequency. In particular for breast cancer diagnosis, there are indications that tumors have impedance characteristics...
Currently, physicians test minimally invasive ablation techniques to determine if they will be acceptable substitutes for surgical removal of primary breast tumors. A study of different electromagnetic hyperthermia ablative therapies, including microwave ablation and radiofrequency ablation, are summarized in this paper. We concluded that further studies are necessary to evaluate its future role as...
Radiofrequency (RF) ablation is receiving increasing attention as treatment for primary and metastatic liver cancer. RF ablation can be performed during open surgery, or minimally invasive through a small incision. An electrode is introduced into the liver tumor, and RF energy is applied. Tissue surrounding the electrode heats up, and is killed above approximately 50 /spl deg/C, where tissue coagulation...
Hepatic resection is the current standard treatment for hepatic malignancies. During hepatic resection part of the liver containing the tumor is surgically removed. This type of surgery is associated with high blood loss of /spl sim/1 L. Blood loss is associated with increased complication rates, prolonged hospital stay and reduced patient survival, especially when transfusion is required. We present...
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