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In the present study we determined whether CpG motifs could be used as an immune adjuvant for the Omp-1 DNA vaccine against Chlamydophila psittaci, based on the major outer membrane protein (MOMP), to induce the protection in specific pathogen free chickens against an intranasal challenge. Six sequences of phosphorothioate-CpG oligodeoxynucleotides (CpG ODNs) with strong immunostimulatory activity...
Examinations were carried out in 46 intensive farms in northern China to investigate avian Chlamydophila psittaci. Five hundred and twenty-five avian sera were selected for examining antibodies to C. psittaci by ELISA. One hundred and fifty-five clinical samples from throat swabs and oviduct tissues were tested for the presence of chlamydial antigen using IDEIA™ PCE chlamydia dual amplification immunoassay,...
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