The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
This study investigated the cellular uptake of fluorescein isothiocyanate-labelled mesoporous silica nanoparticles (FITC-MSNs), amine-functionalised FITC-MSNs (AP-FITC-MSNs) and their gallic acid (GA)-loaded counterparts. Mesoporous silica nanoparticles were labelled with fluorescein isothiocyanate, functionalised by 3-aminopropyltriethoxysilane (APTES) (AP-FITC-MSNs) and then loaded by GA. All nanoparticles...
Nanoparticles are increasingly being recognised for their potential utility in biomedicine. Here, the authors present a low-temperature, solvothermal method to synthesise zinc oxide (ZnO) nanorods using ZnO nanoparticles as precursors, with the addition of low-density polyethylenimine (PEI). This surfactant, which is in regular use in biology, has a double advantage: (i) it catalyses the synthesis...
Iron oxide nanoparticles(Fe3O4 NPs) have recently received increasing interest in the biotechnology and life science. However, little is known about the nanoneurotoxicity of Fe3O4 NPs following exposure to neurons. This study was to elucidate the cytotoxicity and its mechanism of Fe3O4 NPs on PC12 cells line which derived from Rattus norvegicus pheochromocytoma. The cell viability was observed by...
A hybrid, nanosized, localized and release-controlled bone morphogenetic protein delivery system consisting of a liposomal core incorporated into a shell of alternating layer-by-layer self-assembled natural polyelectrolytes has been formulated. Hydrophilic, monodisperse, spherical and stable cationic nanoparticles with an extended shelf-life allowing immediate protein loading prior to clinical administration...
Carbon nanotubes represent a new class of gene transporters potentially useful for future in vitro and in vivo gene delivery applications. The aim of this study was to modify the surfaces of carbon nanotubes (CNTs) with polyamidoamine dendrimer (PAMAM) in order to reduce the cytotoxicity and enhance the cellular uptake of the nanoparticles. In this study, we have prepared and characterized the PAMAM...
Realgar, one of mineral drugs in Chinese traditional medicines has attracted an increasing attention because of its prominent anti-tumor effect. However, new challenges for improving its bioavailability has to be faced. Our previous studies have demonstrated that realgar nanoparticles may provide a less toxic agent for anti-neoplasia by suppressing angiogenesis. In the present study, we improved milling...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.