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The efficacy of spinosad against adult fleas (Ctenocephalides felis) on cats was evaluated in two separate controlled, blinded studies—one to determine flea knockdown and speed of flea kill (SOFK) on experimentally infested cats, another to assess the ability of spinosad to prevent flea infestations in a simulated home environment (SHE) study design. In each study, pre-treatment live flea counts were...
Invasive fungal infections (IFIs) constitute an important cause for morbidity and mortality in immunocompromised pediatric patients [1]. Despite substantial achievements, the prevention and treatment of IFIs are still limited by the facts that not all antifungal agents are approved in the pediatric population, the appropriate dosage of these drugs has not been established for all age groups, and postmarketing...
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