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Combination vaccines simplify vaccination visits and improve coverage and timeliness. DTaP5-HB-IPV-Hib is a new investigational, fully-liquid, combination vaccine designed to protect against 6 infectious diseases, including 5 pertussis antigens and OMPC instead of PT as conjugated protein for Hib component.In this multicenter, double-blind, comparator-controlled, Phase III study (NCT01480258) conducted...
The aim of this study was to evaluate the safety and immunogenicity of DTPa–HBV and Hib vaccines given mixed or separately to 360 healthy infants at 2, 4, and 6 months of age.Immune memory was assessed in lower responders (post-primary anti-PRP <0.545μg/ml), through administration of plain polyribosylribitol phosphate (PRP) at 12–15 months. All subjects received a DTPa–HBV/Hib booster at 18–19...
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