Search results for: Chia-Chu Chiang

Items from 1 to 20 out of 43 results

article

Neural recruitment by ephaptic coupling in epilepsy

Rajat S. Shivacharan, Chia‐Chu Chiang, Xile Wei, Muthumeenakshi Subramanian, more

Epilepsia > 62 > 7 > 1505 - 1517

Objective One of the challenges in treating patients with drug‐resistant epilepsy is that the mechanisms of seizures are unknown. Most current interventions are based on the assumption that epileptic activity recruits neurons and progresses by synaptic transmission. However, several experimental studies have shown that neural activity in rodent hippocampi can propagate independently of synaptic transmission...

article

Slow periodic activity in the longitudinal hippocampal slice can self‐propagate non‐synaptically by a mechanism consistent with ephaptic coupling

Chia‐Chu Chiang, Rajat S. Shivacharan, Xile Wei, Luis E. Gonzalez‐Reyes, more

The Journal of Physiology > 597 > 1 > 249 - 269

Key points Slow periodic activity can propagate with speeds around 0.1 m s⁻¹ and be modulated by weak electric fields. Slow periodic activity in the longitudinal hippocampal slice can propagate without chemical synaptic transmission or gap junctions, but can generate electric fields which in turn activate neighbouring cells. Applying local extracellular electric fields with amplitude in the range...

chapter

On the Design and Implementation of Parallel Programs Through Coordination

Chia-Chu Chiang, Roger Lee, Hae-Sool Yang

Lecture Notes in Computer Science > Software Engineering Research and Applications > Parallel and Distributed Computing > 156-170

The current state of art in existing middleware technologies does not support the development of distributed applications that need processes to complete a task collaboratively. What is needed in the next generation of middleware is synergy of heterogeneity, distribution, communication, and coordination. We are proposing to augment the existing middleware technologies to provide collaboration support...

chapter

An Implementation of a Framework for Open Distributed Computing

Chia-Chu Chiang

Lecture Notes in Computer Science > Algorithms and Architectures for Parallel Processing > Performance of Parallel Distributed Computing Systems > 569-579

In the sequential model of programming, instructions in a program are executed sequentially. Existing programming languages are mainly designed for the sequential model. As the programming paradigm shifts from the sequential to distributed computing, existing sequential programming languages have their limitations. Nevertheless, the sequential languages are the languages which most of programmers...

chapter

An Approach Using Formal Concept Analysis to Object Extraction in Legacy Code

Chia-Chu Chiang, Roger Lee

Studies in Computational Intelligence > Software Engineering, Artificial Intelligence, Networking and Parallel/Distributed Computing > 169-178

Summary Formal concept analysis is a well-known technique for identifying groups of objects in software with common sets of attributes. The objects can be procedures, functions, and modules. In this paper, we are proposing an approach using formal concept analysis to extract objects in a non-object oriented programs. We define an object as a set of data and its associated methods encapsulated in a...

chapter

Layering MDA: Applying Transparent Layers of Knowledge to Platform Independent Models

Oliver Strong, Chia-Chu Chiang, Haeng-Kon Kim, Byeongdo Kang, more

Studies in Computational Intelligence > Software Engineering, Artificial Intelligence, Networking and Parallel/Distributed Computing > 191-199

Model Driven Architecture is a system that holds promise for software engineers, but intimidates them also. This is due to the fact that in order to fully take advantage of MDA engineers must be fluent in UML as well as the languages used to translate their PIM’s into executable. Though UML has been in existence since the mid 1990’s its use for communication among people is eased by shared understanding...

chapter

Concurrency and Time in Role-Based Access Control

Chia-Chu Chiang, Coskun Bayrak

Communications in Computer and Information Science > Advances in Information Security and Its Application > Security Protocol and Its Application > 37-42

Role-based access control (RBAC) has been proposed as an alternative solution for expressing access control policies. The generalized temporal RBAC (GTRBAC) extends RBAC by adding time in order to support timed based access control policies. However, GTRBAC does not address certain issues of concurrency such as, synchronization. We propose an approach to the expressions of time and concurrency in...

chapter

Implementing a Coordination Algorithm for Parallelism on Heterogeneous Computers

Hao Wu, Chia-Chu Chiang

Communications in Computer and Information Science > Software Engineering, Business Continuity, and Education > 228-236

Writing parallel programs is not a simple task. Especially, writing parallel programs for a heterogeneous computing environment is even more difficult. In this paper, a coordination algorithm is implemented to support programmers to write implicitly parallel programs in a heterogeneous computing environment. The programs can be written in a sequential programming language that the programmers are...

article

Seizure reduction through interneuron-mediated entrainment using low frequency optical stimulation

Thomas P. Ladas, Chia-Chu Chiang, Luis E. Gonzalez-Reyes, Theodore Nowak, more

Experimental Neurology > 2015 > 269 > Complete > 120-132

Low frequency electrical stimulation (LFS) can reduce neural excitability and suppress seizures in animals and patients with epilepsy. However the therapeutic outcome could benefit from the determination of the cell types involved in seizure suppression. We used optogenetic techniques to investigate the role of interneurons in LFS (1Hz) in the epileptogenic hippocampus. Optical low frequency stimulation...

article

Parallelizing fully homomorphic encryption for a cloud environment

Ryan Hayward, Chia-Chu Chiang

Journal of Applied Research and Technology > 2015 > 13 > 2 > 245-252

Cloud computing is a boon for both business and private use, but data security concerns slow its adoption. Fully homomorphic encryption (FHE) offers the means by which the cloud computing can be performed on encrypted data, obviating the data security concerns. FHE is not without its cost, as FHE operations take orders of magnitude more processing time and memory than the same operations on unencrypted...

article

Suppression of acute seizures by theta burst electrical stimulation of the hippocampal commissure using a closed-loop system

Boon Hong Siah, Chia-Chu Chiang, Ming-Shaung Ju, Chou-Ching K. Lin

Brain Research > 2014 > 1593 > Complete > 117-125

This study investigated the effects of electrical stimulation with theta burst stimulation (eTBS) on seizure suppression. Optimal parameters of eTBS were determined through open-loop stimulation experiments and then implemented in a close-loop seizure control system. For the experiments, 4-aminopyridine (4-AP) was injected into the right hippocampus of Sprague–Dawley rats to induce an acute seizure...

chapter

Parallelizing Fully Homomorphic Encryption

Ryan Hayward, Chia Chu Chiang

2014 International Symposium on Computer, Consumer and Control > 721 - 724

2014 International Symposium on Computer, Consumer and Control (IS3C)

As cloud computing has grown increasingly prevalent, the privacy of data on the cloud becomes an issue. Encryption is an effective way to enforce data privacy. However most of existing encryption schemes require data to be decrypted for computations where data becomes vulnerable for data intrusion. Homomorphic encryption is an encryption scheme which allows for computations on encrypted data and obtains...

chapter

Software development concerns in the building of service-oriented based enterprise systems

Chia-Chu Chiang

15th IEEE/ACIS International Conference on Software Engineering, Artificial Intelligence, Networking and Parallel/Distributed Computing (SNPD) > 1 - 5

2014 15th IEEE/ACIS International Conference on Software Engineering, Artificial Intelligence, Networking and Parallel/Distributed Computing (SNPD)

Traditional information technology architectures are static and centralized. As such, they are not flexible enough for companies to quickly change their business functions in order to meet evolving business needs. Service oriented architecture (SOA) has been a technology that enables companies to manage their business functions flexibly and efficiently. In our opinion, SOA should be not only enhancing...

article

TRPV1 antagonist capsazepine suppresses 4-AP-induced epileptiform activity in vitro and electrographic seizures in vivo

Luis E. Gonzalez-Reyes, Thomas P. Ladas, Chia-Chu Chiang, Dominique M. Durand

Experimental Neurology > 2013 > 250 > Complete > 321-332

Transient receptor potential vanilloid 1 (TRPV1) is a cation-permeable ion channel found in the peripheral and central nervous systems. The membrane surface expression of TRPV1 is known to occur in neuronal cell bodies and sensory neuron axons. TRPV1 receptors are also expressed in the hippocampus, the main epileptogenic region in the brain. Although, previous studies implicate TRPV1 channels in the...

chapter

An Architecture for Parallelizing Fully Homomorphic Cryptography on Cloud

Ryan Hayward, Chia-Chu Chiang

2013 Seventh International Conference on Complex, Intelligent, and Software Intensive Systems > 72 - 77

2013 7th International Conference on Complex, Intelligent, and Software Intensive Systems (CISIS)

Fully homomorphic cryptography allows arbitrary computations to be carried out on encrypted data and an encrypted result to be obtained which encrypts the result of the computation performed on the plaintext. The first fully homomorphic cryptosystem was introduced by Gentry in the summer of 2009. In this research, we are interested in evaluating the performance of Gentry's algorithm applied to cloud...

article

High frequency stimulation can suppress globally seizures induced by 4-AP in the rat hippocampus: An acute in vivo study

Chia-Chu Chiang, Chou-Ching K. Lin, Ming-Shaung Ju, Dominique M. Durand

Brain Stimulation > 2013 > 6 > 2 > 180-189

High frequency stimulation (HFS) on the hippocampus can locally suppress epileptiform activity in-vitro and decrease seizure frequency in vivo. In-vitro HFS on the ventral commissural tract, a novel target, was shown to block the axonal conduction and suppress activity in the CA1 and CA3 neuron.To study the spatial extent of seizure suppression by HFS applied on the tract and focus site in an in vivo...

chapter

A method for fetal assessment using data mining and machine learning

Wes Copeland, Chia-Chu Chiang

2012 International Conference on Information Security and Intelligent Control > 341 - 344

2012 International Conference on Information Security and Intelligence Control (ISIC)

If a woman is pregnant, it is important for both her and her doctor/clinician to be aware if there are problems with the developing fetus. There are currently ways to discover problems using both noninvasive and invasive techniques. The University of Arkansas for Medical Sciences (UAMS) has recently developed a noninvasive system called the Squid Array for Reproductive Assessment (SARA) that can be...

chapter

Securing Enterprise Mobile Information

Wes Copeland, Chia-Chu Chiang

2012 International Symposium on Computer, Consumer and Control > 80 - 83

2012 International Symposium on Computer, Consumer and Control (IS3C)

Advanced technologies used on mobile devices has brought us to the attention of mobile information security. This paper deals with the mobile phone information security of enterprises. The paper begins with the definition of information security, types of threats and vulnerabilities, and impacts of security breaches. An enterprise mobile information security management environment is presented to...

chapter

Encapsulating Coordination in the Context of Distributed Systems

Chia-Chu Chiang

2012 International Symposium on Computer, Consumer and Control > 76 - 79

2012 International Symposium on Computer, Consumer and Control (IS3C)

It has been widely agreed that writing programs for heterogeneous distributed computing is complex and difficult. Programmers are required to deal with the low-level details of synchronization, heterogeneity, and communication. The primary goal of this research is to simplify the programming by making these complexities hidden from the programmers. Thus, the programmers can focus on the computational...

article

Introduction

Donghwi Lee, Chia-Chu Chiang, Mal Rey Lee, Herbert Kuchen, more

Telecommunication Systems > 2012 > 51 > 2-3 > 93-93

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INFONA - science communication portal

Search results for: Chia-Chu Chiang

Neural recruitment by ephaptic coupling in epilepsy

Slow periodic activity in the longitudinal hippocampal slice can self‐propagate non‐synaptically by a mechanism consistent with ephaptic coupling

On the Design and Implementation of Parallel Programs Through Coordination

An Implementation of a Framework for Open Distributed Computing

An Approach Using Formal Concept Analysis to Object Extraction in Legacy Code

Layering MDA: Applying Transparent Layers of Knowledge to Platform Independent Models

Concurrency and Time in Role-Based Access Control

Implementing a Coordination Algorithm for Parallelism on Heterogeneous Computers

Seizure reduction through interneuron-mediated entrainment using low frequency optical stimulation

Parallelizing fully homomorphic encryption for a cloud environment

Suppression of acute seizures by theta burst electrical stimulation of the hippocampal commissure using a closed-loop system

Parallelizing Fully Homomorphic Encryption

Software development concerns in the building of service-oriented based enterprise systems

TRPV1 antagonist capsazepine suppresses 4-AP-induced epileptiform activity in vitro and electrographic seizures in vivo

An Architecture for Parallelizing Fully Homomorphic Cryptography on Cloud

High frequency stimulation can suppress globally seizures induced by 4-AP in the rat hippocampus: An acute in vivo study

A method for fetal assessment using data mining and machine learning

Securing Enterprise Mobile Information

Encapsulating Coordination in the Context of Distributed Systems

Introduction

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