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Approximately 2–5 % of patients with breast cancer (BC) develop leptomeningeal metastasis (LM). 103 consecutive patients with BC were diagnosed with LM and initially treated with intra-CSF liposomal cytarabine from 2007 to 2011 at a single institution. Correlations were determined with respect to patient characteristics and BC subtype with regard to overall survival (OS). At LM diagnosis, 61 % of...
L’ouverture du protocole MIITOP-0607, étudiant l’efficacité de l’association topotécan et [ 131 I]-mIBG à dose myélosupressive chez des enfants présentant un neuroblastome réfractaire, nécessitait d’évaluer l’exposition du personnel et des accompagnants afin d’obtenir l’aval nécessaire de l’Autorité de sûreté nucléaire (ASN). L’objectif de notre étude était de quantifier l’exposition du personnel...
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