Search results for: Chen Liang

Items from 1 to 20 out of 684 results

article

Germline assessment for alloHSCT candidates over 50 years: A ‘Fast‐Track’ screening in myeloid neoplasms

Sara Torres‐Esquius, Francisco Beas, Tzu Hua Chen‐Liang, Helena Pomares, more

British Journal of Haematology > 205 > 2 > 503 - 509

Patients aged 50 or above diagnosed with myeloid neoplasms (MNs) are typically not candidates for germline testing. However, approximately 8% carry pathogenic germline variants. Allogeneic haematopoietic stem cell transplantation (alloHSCT) remains an option for those aged over 50; neglecting germline testing could mask the risk for relative donor cell‐derived MN. We propose a germline‐augmented somatic...

article

Surface‐Based Multimeric Aptamer Generation and Bio‐Functionalization for Electrochemical Biosensing Applications

Seyed Vahid Hamidi, Arash Khorrami Jahromi, Imman I. Hosseini, Roozbeh Siavash Moakhar, more

Angewandte Chemie > 136 > 32 > n/a - n/a

Multimeric aptamers have gained more attention than their monomeric counterparts due to providing more binding sites for target analytes, leading to increased affinity. This work attempted to engineer the surface‐based generation of multimeric aptamers by employing the room temperature rolling circle amplification (RCA) technique and chemically modified primers for developing a highly sensitive and...

article

Surface‐Based Multimeric Aptamer Generation and Bio‐Functionalization for Electrochemical Biosensing Applications

Seyed Vahid Hamidi, Arash Khorrami Jahromi, Imman I. Hosseini, Roozbeh Siavash Moakhar, more

Angewandte Chemie International Edition > 63 > 32 > n/a - n/a

article

Construction of self‐healing gallium (III)‐cross‐linked konjac glucomannan/polyacrylamide hydrogels for efficiently killing bacteria and accelerating wound healing

Zhi‐Hao Xu, Ping Sun, Xue Zhang, Jia‐Yin Zhang, more

Journal of Applied Polymer Science > 141 > 32 > n/a - n/a

Gallium ions have a special action mechanism that interferes bacterial iron metabolism, thereby possessing great potential for the treatment of bacterial infections. In this work, gallium ions‐cross‐linked konjac glucomannan/polyacrylamide (KGM/PAM/Ga³⁺) hydrogels are successfully constructed with satisfactory swelling ability, appropriate mechanical properties and adjustable degradation performance...

article

Photo Switchable 4D Printing Remotely Controlled Responsive and Mimetic Deformation Shape Memory Polymer Nanocomposites

Shiwei Feng, Xuelin Peng, Jingjing Cui, Ruiqi Feng, more

Advanced Functional Materials > 34 > 28 > n/a - n/a

Photo‐triggered shape morphing structures can be found in myriads of areas. Utilizing light as a switch can effectively control and regulate the precise deformation of structures. However, the integration of photo‐switching functions in shape‐morphing structures with complex geometries remains a challenge. Here, photoswitchable digital light processing based 4D printing high‐resolution and highly...

article

Toughening Hydrogels with Fibrillar Connected Double Networks

Yu‐Huang Fang, Chen Liang, Ville Liljeström, Zhong‐Peng Lv, more

Advanced Materials > 36 > 27 > n/a - n/a

Biological tissues, such as tendons or cartilage, possess high strength and toughness with very low plastic deformations. In contrast, current strategies to prepare tough hydrogels commonly utilize energy dissipation mechanisms based on physical bonds that lead to irreversible large plastic deformations, thus limiting their load‐bearing applications. This article reports a strategy to toughen hydrogels...

article

Projection Stereolithography 3D Printing High‐Conductive Hydrogel for Flexible Passive Wireless Sensing

Yongding Sun, Jin Cui, Shiwei Feng, Jingjing Cui, more

Advanced Materials > 36 > 25 > n/a - n/a

Hydrogel‐based electronics have inherent similarities to biological tissues and hold potential for wearable applications. However, low conductivity, poor stretchability, nonpersonalizability, and uncontrollable dehydration during use limit their further development. In this study, projection stereolithography 3D printing high‐conductive hydrogel for flexible passive wireless sensing is reported. The...

article

Examining the role of artificial intelligence in advancing pollution reduction strategies

Fang Liu, Chen Liang

Managerial and Decision Economics > 45 > 5 > 3068 - 3079

This study is based on the panel data from 2006 to 2020 to explore the relationship between artificial intelligence (AI) and pollution emission. The study demonstrates a notable and statistically significant reduction in pollution emission intensity attributable to AI. This finding is robust, holding up under various sensitivity analyses and addressing endogeneity using instrumental variable techniques...

article

Differences in the prevalence of uveitis between Crohn's disease and ulcerative colitis: A systematic review and meta‐analysis

Haowen Lin, Jiaqing Zhang, Chen Liang, Dongxuan Wu, more

Acta Ophthalmologica > 102 > 4 > e485 - e492

Purpose Uveitis is one of the ocular manifestations of inflammatory bowel disease (IBD) that is often overlooked and has been considered a sign of severe IBD. As typical subtypes of IBD, differences exist in the prevalence of uveitis between Crohn's disease (CD) and ulcerative colitis (UC). Our study systematically assessed differences in the prevalence of uveitis between CD and UC. Methods The...

article

Unveiling unique alternative splicing responses to low temperature in Zoysia japonica through ZjRTD1.0, a high‐quality reference transcript dataset

Zhi‐Hao Wu, Liang‐Liang He, Cong‐Cong Wang, Chen Liang, more

Physiologia Plantarum > 176 > 2 > n/a - n/a

Inadequate reference databases in RNA‐seq analysis can hinder data utilization and interpretation. In this study, we have successfully constructed a high‐quality reference transcript dataset, ZjRTD1.0, for Zoysia japonica, a widely‐used turfgrass with exceptional tolerance to various abiotic stress, including low temperatures and salinity. This dataset comprises 113,089 transcripts from 57,143 genes...

article

Stachydrine represses the proliferation and enhances cell cycle arrest and apoptosis of breast cancer cells via PLA2G2A/DCN axis

Zhen Zhai, Tianlong Mu, Lina Zhao, Dongsheng Zhu, more

Chemical Biology & Drug Design > 103 > 1 > n/a - n/a

Considering the therapeutic efficacy of Stachydrine on breast cancer (BC), this study aims to decipher the relevant mechanism. The effects of Stachydrine on BC cell viability, proliferation and apoptosis were firstly investigated. Then, Bioinformatics was applied to sort out the candidate interacting with Stachydrine as well as its expression and downstream target in BC. Relative expressions of genes...

article

Dual Barriers: Examining Digital Access and Travel Burdens to Hospital Maternity Care Access in the United States, 2020

PEIYIN HUNG, MARION GRANGER, NANSI BOGHOSSIAN, JIANI YU, more

The Milbank Quarterly > 101 > 4 > 1327 - 1347

Context With the increases in nationwide hospital maternity unit closures, there is a greater need for telehealth services for the supervision, evaluation, and management of prenatal and postpartum care. However, challenges in digital access persist. We examined associations between driving time to hospital maternity units and digital access to understand whether augmenting digital access and...

article

Programmable and Self‐Healable Liquid Crystal Elastomer Actuators Based on Halogen Bonding

Hongshuang Guo, Chen Liang, Tero‐Petri Ruoko, Henning Meteling, more

Angewandte Chemie International Edition > 62 > 43 > n/a - n/a

Shape‐changing polymeric materials have gained significant attention in the field of bioinspired soft robotics. However, challenges remain in versatilizing the shape‐morphing process to suit different tasks and environments, and in designing systems that combine reversible actuation and self‐healing ability. Here, we report halogen‐bonded liquid crystal elastomers (LCEs) that can be arbitrarily shape‐programmed...

article

Programmable and Self‐Healable Liquid Crystal Elastomer Actuators Based on Halogen Bonding

Hongshuang Guo, Chen Liang, Tero‐Petri Ruoko, Henning Meteling, more

Angewandte Chemie > 135 > 43 > n/a - n/a

article

Flocculation efficiency of phosphorylated hemoglobin on kaolin and hematite systems

Changhoon Lee, Rafael A. Garcia, Lorelie P. Bumanlag, Chen Liang

Journal of Applied Polymer Science > 140 > 37 > n/a - n/a

Hemoglobin recovered from slaughterhouse blood has proven to be an effective flocculant of negatively charged particulate contaminants, but it is ineffective against positively charged contaminants. Phosphorylation is useful for modifying proteins to increase the number of negatively charged sites. Dry‐heat phosphorylation and chemical phosphorylation were applied to hemoglobin. The kaolin/hematite...

article

Sequential‐Stimuli Induced Stepwise‐Response of Pyridylpyrenes

Yufeng Zhang, Shuai Zhang, Chen Liang, Junqing Shi, more

Advanced Materials > 35 > 32 > n/a - n/a

Stimuli‐responsive materials, especially multi‐stimuli‐responsive materials, can sense external stimuli such as light, heat, and force, have shown great potential in drug delivery, data storage, encryption, energy‐harvesting, and artificial intelligence. Conventional multi‐stimuli‐responsive materials are sensitive to each independent stimulus, causing losses in the diversity and accuracy of the identification...

article

Interface modified Si@SiO₂/PVDF composite dielectrics with synchronously ameliorative dielectric and mechanical properties

Fanrong Kong, Wenying Zhou, Weiwei Peng, Chen Liang, more

Journal of Applied Polymer Science > 140 > 31 > n/a - n/a

To efficaciously decrease dielectric loss while still synchronously harvesting a high dielectric constant (ε′) and breakdown strength (E_b), as well as good mechanical properties in silicon (Si)/poly(vinylidene fluoride) (PVDF), in this work, the core@shell structured Si@silicon dioxide (SiO₂) particles were first prepared via a high temperature oxidation, and subsequently incorporated into the PVDF...

article

Repeatedly Recyclable 3D Printing Catalyst‐Free Dynamic Thermosetting Photopolymers

Jingjing Cui, Fukang Liu, Zhe Lu, Shiwei Feng, more

Advanced Materials > 35 > 20 > n/a - n/a

Photo‐curing 3D printing technology has promoted the advanced manufacturing in various fields, but has exacerbated the environmental crisis by the demand for the chemically cross‐linked thermosetting photopolymers. Here, the authors report a generic strategy to develop catalyst‐free dynamic thermosetting photopolymers, based on photopolymerization and transesterification, that can enable users to...

article

NOTCH1 mutation in chronic lymphocytic leukaemia is associated with an enhanced cell cycle G1/S transition and specific cyclin overexpression: Preclinical ground for targeted inhibition

Salvador Carrillo‐Tornel, Tzu Hua Chen‐Liang, María Zurdo, Anna Puiggros, more

British Journal of Haematology > 201 > 3 > 470 - 479

Studies prior to next‐generation sequencing (NGS) showed that the frequent indolent course of chronic lymphocytic leukaemia (CLL) is related to most cells remaining quiescent in the G₀–G₁ cell cycle phase, due to the expression of dysregulated cyclin genes. Of note, the activating nature of the NOTCH1 mutation in T lymphoblastic leukaemia also drives the dysregulation of cell cycle genes. Our goal...

article

Inserting Single‐Atom Zn by Tannic Acid Confinement To Regulate the Selectivity of Pd Nanocatalysts for Hydrogenation Reactions

Sha‐Sha Zhang, Jun Yi, Tai Cao, Jian‐Ping Guan, more

Small > 19 > 10 > n/a - n/a

Precisely controlling the selectivity of nanocatalysts has always been a hot topic in heterogeneous catalysis but remains difficult owing to their complex and inhomogeneous catalytic sites. Herein, an effective strategy to regulate the chemoselectivity of Pd nanocatalysts for selective hydrogenation reactions by inserting single‐atom Zn into Pd nanoparticles is reported. Taking advantage of the tannic...

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INFONA - science communication portal

Search results for: Chen Liang

Germline assessment for alloHSCT candidates over 50 years: A ‘Fast‐Track’ screening in myeloid neoplasms

Surface‐Based Multimeric Aptamer Generation and Bio‐Functionalization for Electrochemical Biosensing Applications

Surface‐Based Multimeric Aptamer Generation and Bio‐Functionalization for Electrochemical Biosensing Applications

Construction of self‐healing gallium (III)‐cross‐linked konjac glucomannan/polyacrylamide hydrogels for efficiently killing bacteria and accelerating wound healing

Photo Switchable 4D Printing Remotely Controlled Responsive and Mimetic Deformation Shape Memory Polymer Nanocomposites

Toughening Hydrogels with Fibrillar Connected Double Networks

Projection Stereolithography 3D Printing High‐Conductive Hydrogel for Flexible Passive Wireless Sensing

Examining the role of artificial intelligence in advancing pollution reduction strategies

Differences in the prevalence of uveitis between Crohn's disease and ulcerative colitis: A systematic review and meta‐analysis

Unveiling unique alternative splicing responses to low temperature in Zoysia japonica through ZjRTD1.0, a high‐quality reference transcript dataset

Stachydrine represses the proliferation and enhances cell cycle arrest and apoptosis of breast cancer cells via PLA2G2A/DCN axis

Dual Barriers: Examining Digital Access and Travel Burdens to Hospital Maternity Care Access in the United States, 2020

Programmable and Self‐Healable Liquid Crystal Elastomer Actuators Based on Halogen Bonding

Programmable and Self‐Healable Liquid Crystal Elastomer Actuators Based on Halogen Bonding

Flocculation efficiency of phosphorylated hemoglobin on kaolin and hematite systems

Sequential‐Stimuli Induced Stepwise‐Response of Pyridylpyrenes

Interface modified Si@SiO₂/PVDF composite dielectrics with synchronously ameliorative dielectric and mechanical properties

Repeatedly Recyclable 3D Printing Catalyst‐Free Dynamic Thermosetting Photopolymers

NOTCH1 mutation in chronic lymphocytic leukaemia is associated with an enhanced cell cycle G1/S transition and specific cyclin overexpression: Preclinical ground for targeted inhibition

Inserting Single‐Atom Zn by Tannic Acid Confinement To Regulate the Selectivity of Pd Nanocatalysts for Hydrogenation Reactions

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