Search results for: Jer-Yiing Houng

Items from 1 to 20 out of 37 results

article

Plasma fatty acid-binding protein 4 (FABP4) level is associated with abnormal QTc interval in patients with stable angina and chronic kidney disease

Chao-Ping Wang, Chia-Chang Hsu, Wei-Chin Hung, Teng-Hung Yu, more

BMC Cardiovascular Disorders > 2019 > 19 > 1 > 1-11

Background Fatty acid-binding protein 4 (FABP4) (also known as adipocyte FABP or adipocyte P2) is expressed in adipocytes, macrophages, and capillary endothelial cells. Previous studies have shown associations among plasma FABP4, insulin resistance, metabolic syndrome, diabetes mellitus, greater coronary plaque burden, coronary artery disease, heart failure, and mortality. However, little is known...

article

Circulating secreted frizzled-related protein 5 and chronic kidney disease in patients with acute ST-segment elevation myocardial infarction

Chao-Ping Wang, Teng-Hung Yu, Cheng-Ching Wu, Wei-Chin Hung, more

Cytokine > 2018 > 110 > C > 367-373

Secreted frizzled-related protein-5 (Sfrp5) known as secreted antagonist binds to Wnt protein. It has been shown to be downregulated by histone acetylation and promoter methylation, and to function as a tumor suppressor gene by inducing apoptosis in renal cell cancer cells. However, its relationship with chronic kidney disease (CKD) has not been well studied. Our objective was to investigate the effect...

article

Association between hippuric acid and left ventricular hypertrophy in maintenance hemodialysis patients

Teng-Hung Yu, Wei-Hua Tang, Yung-Chuan Lu, Chao-Ping Wang, more

Clinica Chimica Acta > 2018 > 484 > C > 47-51

Left ventricular hypertrophy (LVH) is one of the most common cardiac abnormalities in patients with end-stage renal disease. Hippuric acid (HA), a harmful uremic toxin, is known to be elevated in patients with uremia, and serum HA levels are associated with neurological symptoms, metabolic acidosis, and accelerated renal damage associated with chronic kidney disease. However, the pathophysiological...

article

Shift work is associated with metabolic syndrome in male steel workers-the role of resistin and WBC count-related metabolic derangements

Yung-Chuan Lu, Chao-Ping Wang, Teng-Hung Yu, I-Ting Tsai, more

Diabetology & Metabolic Syndrome > 2017 > 9 > 1 > 1-7

Aims There is increasing evidence linking a shift work schedule with various adverse health effects. The present study aimed to examine the relationship between shift work and the metabolic syndrome (MetS) in male steel workers, and also the possible mechanism of shift work-related metabolic derangements. Methods A total of 1732 men aged 42 ± 8 years were enrolled in this cross-sectional study,...

article

Glossogyne tenuifolia (Hsiang-ju) extract suppresses T cell activation by inhibiting activation of c-Jun N-terminal kinase

Jer-Yiing Houng, Tzong-Shyuan Tai, Shu-Ching Hsu, Hsia-Fen Hsu, more

Chinese Medicine > 2017 > 12 > 1 > 1-10

Background Glossogyne tenuifolia (GT) (Hsiang-ju) is a Chinese herbal medicine previously exhibited an anti-inflammatory activity. This study aimed to investigate the effect of GT ethanol extract (GTE) on T cell-mediated adaptive immunity. Methods Human peripheral blood mononuclear cells (PBMCs) and Jurkat T cells were activated by phytohemagglutinin in the presence of various doses (3.13–50 μg/mL)...

article

Antioxidant and anti-inflammatory activities of Lonicera japonica Thunb. var. sempervillosa Hayata flower bud extracts prepared by water, ethanol and supercritical fluid extraction techniques

Hsia-Fen Hsu, Pei-Chi Hsiao, Tzu-Chen Kuo, Shu-Tuan Chiang, more

Industrial Crops and Products > 2016 > 89 > C > 543-549

Lonicera japonica Thunberg (LJ) has long been used as an antipyretic, anti-inflammatory and anti-infectious agent in East Asia. The subspecies L. japonica Thunb. var. sempervillosa Hayata (LJv) is a variant that mainly grows in Taiwan. This study examined the antioxidant and anti-inflammatory activities of the extracts from the flower buds of these two species. The extracts were obtained by three...

article

Extraction of lignans from the seed of Schisandra chinensis by supercritical fluid extraction and subsequent separation by supercritical fluid simulated moving bed

Chih-Hsiung Lin, Hsin-Wei Lin, Jau-Yann Wu, Jer-Yiing Houng, more

The Journal of Supercritical Fluids > 2015 > 98 > Complete > 17-24

In this study, the lignans in the seed of Schisandra chinensis were extracted by supercritical fluid extraction (SFE), and the lignans in the obtained seed oil were subsequently separated by simulated moving bed (SMB) chromatography with supercritical fluid as the desorbent (SF-SMB). Four lignans: Schisandrol A, Schisandrol B, Schisandrin A and Schisandrin B, in the seed oil are monitored to study...

article

Evaluation of a rapid quantitative determination method of PSA concentration with gold immunochromatographic strips

Cheng-Ching Wu, Hung-Yu Lin, Chao-Ping Wang, Li-Fen Lu, more

BMC Urology > 2015 > 15 > 1 > 1-7

Background Prostate cancer remains the most common cancer in men. Qualitative or semi-quantitative immunochromatographic measurements of prostate specific antigen (PSA) have been shown to be simple, noninvasive and feasible. The aim of this study was to evaluate an optimized gold immunochromatographic strip device for the detection of PSA, in which the results can be analysed using a Chromogenic Rapid...

article

Pretreatment circulating monocyte count associated with poor prognosis in patients with oral cavity cancer

Yu‐Duan Tsai, Chao‐Ping Wang, Chih‐Yu Chen, Li‐Wen Lin, more

Head & Neck > 36 > 7 > 947 - 953

BackgroundThe purpose of this study was to investigate whether the pretreatment total and differential leukocyte counts can predict the prognosis of patients with oral cavity cancer. MethodsIn a retrospective analysis of patients treated between 2004 and 2011, medical records of 202 patients with oral cavity cancer were evaluated. ResultsPatients with oral cavity cancer, the peripheral total white...

article

Antioxidant, anti-inflammatory, and anti-proliferative activities of extracts from different parts of farmed and wild Glossogyne tenuifolia

Yu-Duan Tsai, Hsia-Fen Hsu, Zi-Hua Chen, Yu-Ting Wang, more

Industrial Crops & Products > 2014 > 57 > Complete > 98-105

The antioxidant, anti-inflammatory, and anti-proliferative properties of extracts from different plant parts of farmed and wild Glossogyne tenuifolia (GT) were compared. Samples were either extracted by n-hexane, ethyl acetate (EA), and methanol (MeOH), respectively. Antioxidant properties were measured by DPPH radical scavenging activity and SOD anion scavenging activity. The DPPH and SOD scavenging...

article

Inhibitory activity on RANKL-mediated osteoclastogenesis of Glossogyne tenuifolia extract

Shih-Wei Wang, Han-Chun Kuo, Hsia-Fen Hsu, Yuan-Kun Tu, more

Journal of Functional Foods > 2014 > 6 > C > 215-223

Receptor activator of nuclear factor kappa B ligand (RANKL)-induced activation of NF-κB and MAPKs signaling pathways is critical to osteoclastogenesis. Glossogyne tenuifolia has been used as an antipyretic, detoxification and anti-inflammatory herb tea in Penghu Island, Taiwan. This study investigated the effects of G. tenuifolia ethanolic extract (GTE) on the formation of RANKL-activating osteoclasts...

article

Luteolin inhibits proliferation of human glioblastoma cells via induction of cell cycle arrest and apoptosis

Yu-Duan Tsai, Han-Jung Chen, Hsia-Fen Hsu, Kang Lu, more

Journal of the Taiwan Institute of Chemical Engineers > 2013 > 44 > 6 > 837-845

Glioblastoma multiforme (GBM) is a highly malignant brain tumor with limited therapeutic options, and high recurrence and mortality rates. In this study, the anti-tumorigenic properties of luteolin on GBM were examined in vitro. Luteolin was isolated from the whole plant of Glossogyne tenuifolia and the chemical structure was determined by its spectroscopic data. The inhibitory effect of luteolin...

article

Polymorphism of angiotensin I-converting enzyme gene is related to oral cancer and lymph node metastasis in male betel quid chewers

Yi-Tien Liu, Li-Wen Lin, Chih-Yu Chen, Chao-Ping Wang, more

Oral Oncology > 2012 > 48 > 12 > 1257-1262

Angiotensin I-converting enzyme (ACE), a type I cell surface zinc metallopeptidase, is differentially expressed in several malignancies and plays a role in tumor cell proliferation, tumor cell migration, angiogenesis, and metastatic behavior. We aimed to investigate the effects of ACE gene (rs1799752) variants on oral cancer risk.Polymerase chain reaction–restriction fragment length polymorphism (PCR-RFLP)...

article

Effect of conjugated linoleic acid supplementation on weight loss and body fat composition in a Chinese population

Shu-Chiun Chen, Yu-Hsien Lin, Hui-Ping Huang, Wan-Ling Hsu, more

Nutrition > 2012 > 28 > 5 > 559-565

Conjugated linoleic acid (CLA) has several benefits, including body fat reduction, as proved in animals. However, the results of CLA-induced body composition alterations in humans are inconsistent, and no related data are available for Chinese populations. This study aimed to determine whether CLA affects body weight (BW) loss and body composition of overweight and obese Chinese subjects.In this randomized,...

article

Surgical results of single-incision transumbilical laparoscopic Roux-en-Y gastric bypass

Chih-Kun Huang, Chi-Hsien Lo, Jer-Yiing Houng, Yaw-Sen Chen, more

Surgery for Obesity and Related Diseases > 2012 > 8 > 2 > 201-207

Conventional laparoscopic Roux-en-Y gastric bypass (LRYGB) has been the reference standard for bariatric surgery but requires 5–7 trocar incisions. We have developed a new procedure—single-incision transumbilical LRYGB (SITU-LRYGB)—that results in minimal scarring and is more cosmetically acceptable. To compare the surgical results and patient satisfaction between 5-port LRYGB and the novel SITU-LRYGB...

article

Optimization of medium composition for improving biomass production of Lactobacillus plantarum Pi06 using the Taguchi array design and the Box-Behnken method

Chin-Fa Hwang, Jen-Han Chang, Jer-Yiing Houng, Cheng-Chih Tsai, more

Biotechnology and Bioprocess Engineering > 2012 > 17 > 4 > 827-834

An immune-enhancing strain, Lactobacillus plantarum Pi06, isolated from a healthy infant was used for biomass production following optimization of the medium in shake-flask culture. Preliminary studies showed that commercial MRS medium and cultivation under static conditions generated higher biomass production than four other tested media with or without a shaking condition. The selected medium composition,...

article

Apoptotic effects of bioactive fraction isolated from Glossogyne tenuifolia on A549 human lung cancer cells

Hsia-Fen Hsu, Yang-Chang Wu, Chi-Chang Chang, Jer-Yiing Houng

Journal of the Taiwan Institute of Chemical Engineers > 2011 > 42 > 4 > 556-562

Our previous study has demonstrated that the ethyl acetate (EA) extract of Glossogyne tenuifolia has strong cytotoxicity toward several human cancer cells including lung cancer cells. In this work, a bioactive fraction (Fr. C) that exhibited significant antiproliferative activity on A549 human lung cancer cells (IC ₅₀ =18.2μg/ml) and had less sensitive effect on MRC-5 normal lung fibroblast...

article

Typhonium blumei extract inhibits proliferation of human lung adenocarcinoma A549 cells via induction of cell cycle arrest and apoptosis

Hsia-Fen Hsu, Kuo-Hung Huang, Kuei-Ju Lu, Shu-Jiau Chiou, more

Journal of Ethnopharmacology > 2011 > 135 > 2 > 492-500

Typhonium blumei Nicolson & Sivadasan is a traditional Chinese medicinal herb endowing with detumescence, detoxification, anti-inflammation activities, and has been used as a folk prescription on anticancer in Taiwan.The purpose of this study is to investigate the inhibitory effect of Typhonium blumei (Tb) extract on the viability of different cancer cells and the apoptotic effect of this extract...

article

PL-136 Laparoscopic Roux-en-Y gastric bypass for the treatment of type II diabetes mellitus with body mass index 25-35 kg/m2, a prospective study

Chih-Kun Huang, Chi-Hsien Lo, Jer-Yiing Houng

Surgery for Obesity and Related Diseases > 2011 > 7 > 3 > 352

article

A Novel Technique for Liver Retraction in Laparoscopic Bariatric Surgery

Chih Kun Huang, Chi-Hsien Lo, Shabbir Asim, Jer-Yiing Houng, more

Obesity Surgery > 2011 > 21 > 5 > 676-679

During bariatric surgery in morbidly obese patients, the surgeon’s operative view is often obscured by the hypertrophic fatty left lobe of the liver. The use of a conventional liver retractor mandates an additional subxiphoid wound, resulting in pain and scar formation, in addition to the risk of iatrogenic liver injury during retractor insertion. To overcome these limitations, we developed a simple,...

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Search results for: Jer-Yiing Houng

Plasma fatty acid-binding protein 4 (FABP4) level is associated with abnormal QTc interval in patients with stable angina and chronic kidney disease

Circulating secreted frizzled-related protein 5 and chronic kidney disease in patients with acute ST-segment elevation myocardial infarction

Association between hippuric acid and left ventricular hypertrophy in maintenance hemodialysis patients

Shift work is associated with metabolic syndrome in male steel workers-the role of resistin and WBC count-related metabolic derangements

Glossogyne tenuifolia (Hsiang-ju) extract suppresses T cell activation by inhibiting activation of c-Jun N-terminal kinase

Antioxidant and anti-inflammatory activities of Lonicera japonica Thunb. var. sempervillosa Hayata flower bud extracts prepared by water, ethanol and supercritical fluid extraction techniques

Extraction of lignans from the seed of Schisandra chinensis by supercritical fluid extraction and subsequent separation by supercritical fluid simulated moving bed

Evaluation of a rapid quantitative determination method of PSA concentration with gold immunochromatographic strips

Pretreatment circulating monocyte count associated with poor prognosis in patients with oral cavity cancer

Antioxidant, anti-inflammatory, and anti-proliferative activities of extracts from different parts of farmed and wild Glossogyne tenuifolia

Inhibitory activity on RANKL-mediated osteoclastogenesis of Glossogyne tenuifolia extract

Luteolin inhibits proliferation of human glioblastoma cells via induction of cell cycle arrest and apoptosis

Polymorphism of angiotensin I-converting enzyme gene is related to oral cancer and lymph node metastasis in male betel quid chewers

Effect of conjugated linoleic acid supplementation on weight loss and body fat composition in a Chinese population

Surgical results of single-incision transumbilical laparoscopic Roux-en-Y gastric bypass

Optimization of medium composition for improving biomass production of Lactobacillus plantarum Pi06 using the Taguchi array design and the Box-Behnken method

Apoptotic effects of bioactive fraction isolated from Glossogyne tenuifolia on A549 human lung cancer cells

Typhonium blumei extract inhibits proliferation of human lung adenocarcinoma A549 cells via induction of cell cycle arrest and apoptosis

PL-136 Laparoscopic Roux-en-Y gastric bypass for the treatment of type II diabetes mellitus with body mass index 25-35 kg/m2, a prospective study

A Novel Technique for Liver Retraction in Laparoscopic Bariatric Surgery

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