Search results for: Hirokazu Taniguchi

Items from 1 to 20 out of 131 results

article

Diagnostic utility and prognostic significance of the Ki‐67 labeling index in diffuse large B‐cell lymphoma transformed from follicular lymphoma: a study of 76 patients

Akiko Miyagi Maeshima, Hirokazu Taniguchi, Yoshikazu Hori, Hanae Ida, more

Pathology International > 71 > 10 > 674 - 681

The diagnosis of histological transformation of follicular lymphoma can be challenging and ambiguous. We investigated the distribution of the Ki‐67 labeling index of histological transformation of follicular lymphoma and determined its cutoff value to predict poor outcomes. The diagnostic criteria for histological transformation were a diffuse pattern of proliferation and a proportion of large lymphoma...

article

Clinicopathological factors and tumor microenvironment markers predicting watch‐and‐wait discontinuation in 82 patients with follicular lymphoma

Sayako Yuda, Akiko Miyagi Maeshima, Hirokazu Taniguchi, Yuta Ito, more

European Journal of Haematology > 107 > 1 > 157 - 165

Objectives In this study, we aimed to determine the clinicopathological factors influencing the treatment‐free period in patients with follicular lymphoma (FL) using a watch‐and‐wait (WW) strategy. Methods We retrospectively assessed histopathological parameters of 82 patients with FL. Results The median time from diagnosis to WW discontinuation was 62 months (range, 3‐138), and median follow‐up...

article

Risk for lymph node metastasis in Epstein–Barr virus‐associated gastric carcinoma with submucosal invasion

Yosuke Tsuji, Tetsuo Ushiku, Tomohiro Shinozaki, Hiroharu Yamashita, more

Digestive Endoscopy > 33 > 4 > 592 - 597

Objectives Epstein–Barr virus‐associated gastric cancer (EBVGC) has been reported to be associated with a low risk for lymph node metastasis (LNM). However, the curative criteria for endoscopic submucosal dissection (ESD) for submucosal EBVGC (pT1b‐EBVGC) remain unclear. Our study aimed to investigate the risk factors for LNM in pT1b‐EBVGC. Methods This was a retrospective multicenter study at...

article

The role of local radiotherapy following rituximab‐containing chemotherapy in patients with transformed indolent B‐cell lymphoma

Kenji Nozaki, Dai Maruyama, Akiko Miyagi Maeshima, Kinuko Tajima, more

European Journal of Haematology > 106 > 2 > 213 - 220

Objectives This study aimed to evaluate the outcomes of local radiotherapy (LRT) in patients with histologic transformation (HT) following rituximab‐containing chemotherapy. Methods We retrospectively analysed 92 patients with biopsy‐confirmed HT undergoing rituximab‐containing chemotherapy at our institution between 2003 and 2015. Results Of the 36 patients with limited‐stage disease at diagnosis...

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A comparison of clinical staging using the Lugano versus Ann Arbor classifications in Japanese patients with Hodgkin lymphoma

Shinichi Makita, Dai Maruyama, Akiko Miyagi Maeshima, Hirokazu Taniguchi, more

Asia‐Pacific Journal of Clinical Oncology > 16 > 3 > 108 - 114

Aims The Lugano classification is a novel staging system for lymphomas established in 2014. In this staging system, ¹⁸F‐fluorodeoxyglucose‐positron emission tomography/computed tomography (FDG‐PET/CT) was formally incorporated into standard staging for FDG‐avid lymphomas, including Hodgkin lymphoma (HL). We retrospectively analyzed patients with HL who were newly diagnosed and treated at our institution...

article

Association of CD204⁺ macrophages with poor outcomes of malignant lymphomas not in remission treated by allogeneic HCT

Akihisa Kawajiri, Shigehisa Kitano, Akiko Miyagi Maeshima, Yoshihiro Inamoto, more

European Journal of Haematology > 103 > 6 > 578 - 587

Objective CD204⁺ tumor‐associated macrophages are associated with adverse outcomes of various malignancies. We performed a study to elucidate the role of CD204⁺ macrophages in allogeneic hematopoietic cell transplantation (allogeneic HCT). Methods In a total of 81 patients who received allogeneic HCT for non‐remission malignant lymphoma, immunohistochemical staining of CD204 using specimens preserved...

article

Cover Image

Akihisa Kawajiri, Shigehisa Kitano, Akiko Miyagi Maeshima, Yoshihiro Inamoto, more

European Journal of Haematology > 103 > 6 > i - i

The cover image is based on the Original Article * Association of CD204⁺ macrophages with poor outcomes of malignant lymphomas not in remission treated by allogeneic HCT by Shigehisa Kitano** et al., https://doi.org/10.1111/ejh.13324.***

article

Long-term outcome after one-stage surgery without preoperative decompression for stage II/III malignant colorectal obstruction: a propensity score-matched analysis

Hiroshi Takeyama, Kimimasa Ikeda, Katsuki Danno, Takahiko Nishigaki, more

International Journal of Colorectal Disease > 2019 > 34 > 11 > 1933-1943

Purpose Whether malignant colorectal obstruction (MCO) after one-stage curative surgery without preoperative decompression has a poor prognosis remains unclear. We assessed long-term outcomes of one-stage surgery without preoperative decompression for stage II/III MCO. Methods We retrospectively enrolled patients with stage II/III colorectal cancer (CRC) between April 2011 and December 2017. Propensity...

article

Robot-assisted laparoscopic surgery after placing a self-expanding metallic stent for malignant rectal obstruction: a case report

Hiroshi Takeyama, Katsuki Danno, Takahiko Nishigaki, Masafumi Yamashita, more

Surgical Case Reports > 2019 > 5 > 1 > 1-5

Background Approximately 20% of colorectal cancer patients show complete or incomplete bowel obstruction as an early symptom. Preoperative nonsurgical decompression such as placing a self-expanding metallic stent for malignant colorectal obstruction has been shown to be effective for reducing perioperative morbidity and mortality. However, there is a lack of published studies reporting robot-assisted...

article

Dose escalation study of amrubicin and cisplatin with concurrent thoracic radiotherapy for limited-disease small cell lung cancer

Midori Shimada, Hiroyuki Yamaguchi, Minoru Fukuda, Hiromi Tomono, more

Cancer Chemotherapy and Pharmacology > 2019 > 84 > 5 > 1059-1064

Background Amrubicin and cisplatin is one of the active regimens used to treat patients with extensive-disease (ED)-small cell lung cancer (SCLC), whereas combined therapy involving chemotherapy and concurrent thoracic radiotherapy is the standard treatment for limited-disease (LD)-SCLC. Purpose This study aimed to determine the maximum tolerated dose (MTD) and dose-limiting toxicities (DLT) of...

article

EBV‐encoded RNA1‐positive cells in the bone marrow specimens of patients with EBV‐negative lymphomas and sarcomas

Yuta Ito, Shinichi Makita, Akiko Miyagi Maeshima, Shunsuke Hatta, more

Pathology International > 69 > 7 > 392 - 397

Epstein‐Barr virus (EBV) infection is associated with pathogenesis of various cancers, including extranodal natural killer/T‐cell lymphoma, nasal type (ENKL). ENKL tumor cells are positive for EBV‐encoded RNA1 (EBER1), which is the most useful marker to identify ENKL tumor cells in histopathology. Currently, EBER1 in situ hybridization (ISH) is recommended to evaluate bone marrow (BM) involvement...

article

Reply to “Utility of Intraoperative Margin Assessment by Frozen Section in Gastric Cancer”

Koki Nakanishi, Shinji Morita, Hirokazu Taniguchi, Sho Otsuki, more

Annals of Surgical Oncology > 2019 > 26 > 11 > 3784-3784

article

EIF3E–RSPO2 and PIEZO1–RSPO2 fusions in colorectal traditional serrated adenoma

Taiki Hashimoto, Reiko Ogawa, Hiroshi Yoshida, Hirokazu Taniguchi, more

Histopathology > 75 > 2 > 266 - 273

Aims Traditional serrated adenoma (TSA) is an uncommon type of colorectal serrated polyp. RSPO fusions, which potentiate WNT signalling, are common and characteristic genetic alterations in TSA. The aim of this study was to further characterise the prevalence and variation of RSPO fusions in TSA. Methods and results Quantitative polymerase chain reaction (PCR) analysis of 99 TSAs revealed overexpression...

article

Clinicopathological characteristics of diffuse large B-cell lymphoma involving small and large intestines: an analysis of 126 patients

Akiko Miyagi Maeshima, Hirokazu Taniguchi, Yuta Ito, Shunsuke Hatta, more

International Journal of Hematology > 2019 > 110 > 3 > 340-346

We analyzed the clinicopathologic characteristics of 136 intestinal diffuse large B-cell lymphomas (DLBCLs) among 126 patients. The DLBCL sites were categorized as: duodenum (n = 23), ileocecal region (n = 63), other small intestine (n = 29), rectum (n = 7), and other large intestine (n = 14). Patients with DLBCLs of the ileocecal region or other small intestine frequently underwent surgery for ileus...

article

Mucosa-associated lymphoid tissue lymphoma with t(11;18)(q21;q21) translocation: long-term follow-up results

Kosuke Toyoda, Akiko Miyagi Maeshima, Junko Nomoto, Tomotaka Suzuki, more

Annals of Hematology > 2019 > 98 > 7 > 1675-1687

Translocation (11;18)(q21;q21) is found in mucosa-associated lymphoid tissue (MALT) lymphoma, resulting in API2/MALT1 gene fusion. It is known that t(11;18)-positive MALT lymphoma shows a tendency to disseminate and be resistant to Helicobacter pylori eradication by antibiotics. However, the prognostic features including recurrence and histological transformation (HT) remain unknown. We conducted...

article

Diagnostic Accuracy and Usefulness of Intraoperative Margin Assessment by Frozen Section in Gastric Cancer

Koki Nakanishi, Shinji Morita, Hirokazu Taniguchi, Sho Otsuki, more

Annals of Surgical Oncology > 2019 > 26 > 6 > 1787-1794

Background Intraoperative frozen examination is clinically important for negative margin confirmation in cancer surgery. We investigated the diagnostic accuracy of frozen-section assessment and risk factors for positive resection margins by studying gastric cancer specimens from 1115 patients treated at our hospital. Methods The results of gastric cancer patients who had undergone intraoperative...

article

Long-Term Outcomes Following Partial Versus Complete Cystectomy in Advanced Colorectal Cancer with Regarding to the Extent of Bladder Invasion

Takefumi Yoshida, Dai Shida, Hirokazu Taniguchi, Shunsuke Tsukamoto, more

Annals of Surgical Oncology > 2019 > 26 > 5 > 1569-1576

Background Two procedures widely performed to treat locally advanced colorectal cancer adherent to the urinary bladder are total cystectomy (as part of pelvic exenteration) and partial cystectomy; however, little is known about outcomes following partial cystectomy. Methods A retrospective database of patients with colorectal cancer involving the urinary bladder who underwent R0 or R1 resection...

article

Metachronous metastasis to inguinal lymph nodes from sigmoid colon adenocarcinoma with abdominal wall metastasis: a case report

Taro Tanabe, Dai Shida, Shunsuke Tsukamoto, Goki Morizono, more

BMC Cancer > 2019 > 19 > 1 > 1-5

Background Inguinal lymph node metastasis from rectum is uncommon but well-known occurrence, whereas that from colon adenocarcinoma is extremely rare. Inguinal lymph node metastasis from colon adenocarcinoma has only been reported in previous cases involving primary tumor invasion of the abdominal wall, or in those involving colon cancer metastasis to external iliac lymph nodes. We describe a case...

article

Reappraisal of the genetic heterogeneity of sessile serrated adenoma/polyp

Hourin Cho, Taiki Hashimoto, Hiroshi Yoshida, Hirokazu Taniguchi, more

Histopathology > 73 > 4 > 672 - 680

Aims Sessile serrated adenoma/polyp (SSA/P) is regarded as a genetically homogeneous entity, with most lesions harbouring the BRAF V600E mutation. The present study aimed to reappraise the genetic heterogeneity of SSA/Ps and its clinicopathological significance. Methods and results We performed next‐generation sequencing of 272 SSA/Ps without dysplasia and evaluated morphological and molecular...

article

Broad ligament hernia successfully repaired by single‐incision laparoscopy: A case report

Hiroshi Takeyama, Yuya Kogita, Takahiko Nishigaki, Masafumi Yamashita, more

Asian Journal of Endoscopic Surgery > 11 > 3 > 274 - 276

A 52‐year‐old woman with a history of two parturitions presented with lower abdominal pain. Multi‐detector CT of the abdomen showed discontinuity of the sigmoid colon near the broad ligament on the left side. We assigned a provisional diagnosis of an internal hernia progressing through a defect in the broad ligament. SILS revealed a total broad ligament defect on the left side but no signs of ischemic,...

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INFONA - science communication portal

Search results for: Hirokazu Taniguchi

Diagnostic utility and prognostic significance of the Ki‐67 labeling index in diffuse large B‐cell lymphoma transformed from follicular lymphoma: a study of 76 patients

Clinicopathological factors and tumor microenvironment markers predicting watch‐and‐wait discontinuation in 82 patients with follicular lymphoma

Risk for lymph node metastasis in Epstein–Barr virus‐associated gastric carcinoma with submucosal invasion

The role of local radiotherapy following rituximab‐containing chemotherapy in patients with transformed indolent B‐cell lymphoma

A comparison of clinical staging using the Lugano versus Ann Arbor classifications in Japanese patients with Hodgkin lymphoma

Association of CD204⁺ macrophages with poor outcomes of malignant lymphomas not in remission treated by allogeneic HCT

Cover Image

Long-term outcome after one-stage surgery without preoperative decompression for stage II/III malignant colorectal obstruction: a propensity score-matched analysis

Robot-assisted laparoscopic surgery after placing a self-expanding metallic stent for malignant rectal obstruction: a case report

Dose escalation study of amrubicin and cisplatin with concurrent thoracic radiotherapy for limited-disease small cell lung cancer

EBV‐encoded RNA1‐positive cells in the bone marrow specimens of patients with EBV‐negative lymphomas and sarcomas

Reply to “Utility of Intraoperative Margin Assessment by Frozen Section in Gastric Cancer”

EIF3E–RSPO2 and PIEZO1–RSPO2 fusions in colorectal traditional serrated adenoma

Clinicopathological characteristics of diffuse large B-cell lymphoma involving small and large intestines: an analysis of 126 patients

Mucosa-associated lymphoid tissue lymphoma with t(11;18)(q21;q21) translocation: long-term follow-up results

Diagnostic Accuracy and Usefulness of Intraoperative Margin Assessment by Frozen Section in Gastric Cancer

Long-Term Outcomes Following Partial Versus Complete Cystectomy in Advanced Colorectal Cancer with Regarding to the Extent of Bladder Invasion

Metachronous metastasis to inguinal lymph nodes from sigmoid colon adenocarcinoma with abdominal wall metastasis: a case report

Reappraisal of the genetic heterogeneity of sessile serrated adenoma/polyp

Broad ligament hernia successfully repaired by single‐incision laparoscopy: A case report

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