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Cells rely on secreted signaling molecules to coordinate essential biological functions including development, metabolism, and immunity. Unfortunately, such signaling processes remain difficult to measure with sufficient chemical specificity and temporal resolution. To address this need, an aptamer‐conjugated hydrogel matrix that enables continuous fluorescent measurement of specific secreted analytes...
Cellular Signaling
Cells communicate through secreted biomolecules, however there are few tools to directly record these signals. In article number 2306704, Chan Ho Park, H. Tom Soh, and co‐workers report that embedding fluorescent aptamer sensors within a biocompatible hydrogel enables tracking of cell‐to‐cell signaling with molecular specificity and high temporal resolution, demonstrated by monitoring...