Search results for: Renato Marco

Items from 1 to 5 out of 5 results

article

HLA‐DPB1 molecular mismatches are risk factors for acute rejection and low 5‐year graft function in first kidney transplants

Renato Marco, Lúcio R. Requião‐Moura, Tamiris R. F. Raimundo, Tuíla B. Mourão, more

HLA > 101 > 3 > 228 - 238

The study aimed to investigate the impact of HLA‐DPB1 allelic and molecular mismatches on the occurrence of acute rejection (AR) and low 5‐year graft function (5Y‐GF) in first kidney transplant (KT) recipients. This is a single center retrospective study of 130 deceased donor KT recipients transplanted between 2014 and 2016. HLA‐DPB1 allelic MM and the following molecular MM (mMM) were analyzed: expression...

article

High soluble HLA‐DQB2 levels in posttransplant serum are associated with kidney graft dysfunction

Karina L Mine, Renato Marco, Tamiris R.F. Raimundo, Julia V. Ernesto, more

International Journal of Immunogenetics > 49 > 2 > 63 - 69

HLA‐DQB2 is a gene of limited polymorphism, with unknown function that presents at least two transcript variants: v1, which encodes the full‐length beta‐chain, and v2, which lacks exon 4 and could give rise to a soluble protein. We previously showed a strong correlation between high v2 expression in preimplantation biopsies (PIB) of kidneys from young (18‐ to 49‐year olds) but not from old, deceased...

article

Prospective randomized study comparing everolimus and mycophenolate sodium in de novo kidney transplant recipients from expanded criteria deceased donor

Alexandra Nicolau Ferreira, Claudia Rosso Felipe, Marina Cristelli, Laila Viana, more

Transplant International > 32 > 11 > 1127 - 1143

The optimal immunosuppressive regimen for recipients of expanded criteria donor (ECD) kidneys has not been identified. In this single‐center study, 171 recipients of ECD kidney transplants were randomized to receive antithymocyte globulin induction, and delayed introduction of reduced dose tacrolimus, prednisone and everolimus (r‐ATG/EVR, n = 88), or mycophenolate (r‐ATG/MPS, n = 83). No cytomegalovirus...

article

Kidney Allocation System for Transplantation in Brazil

Suelen Bianca Stopa Martins, Bruna Araujo Ferreira, Vanessa Ayres Carneiro Gonçalves, Renato Marco, more

Current Transplantation Reports > 2019 > 6 > 3 > 209-213

Purpose of Review Worldwide allocation systems are subjected to regulatory and ethical unique themes prevailing under the local socioeconomic and health care system. We sought to describe kidney allocation system, local transplant regulatory environment, and some general information concerning reimbursement in Brazil. Recent Findings Under a universal health care program, the national transplant...

article

P042 A unique combination of two self-amino acids explains the reactivity of an anti-HLA-b∗18:01 antibody produced by a patient carrying the HLA-B∗18:05 allele

Renato Marco, Alberto C. Lima, Noemi F. Pereira, Julia Temin, more

Human Immunology > 2017 > 78 > S > 85

The purpose of the present communication is to report a new epitope that explains the reaction against HLA-B∗18:01 of an antibody produced by an individual carrying HLA-B∗18:05. This reactivity was detected in the Luminex-single antigen assay (LSA) and could not be explained by the HLA MatchMaker algorithm. Comparison between amino acid sequences in alfa-1, −2 and −3 domains of the two B∗18 alleles...

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Search results for: Renato Marco

HLA‐DPB1 molecular mismatches are risk factors for acute rejection and low 5‐year graft function in first kidney transplants

High soluble HLA‐DQB2 levels in posttransplant serum are associated with kidney graft dysfunction

Prospective randomized study comparing everolimus and mycophenolate sodium in de novo kidney transplant recipients from expanded criteria deceased donor

Kidney Allocation System for Transplantation in Brazil

P042 A unique combination of two self-amino acids explains the reactivity of an anti-HLA-b∗18:01 antibody produced by a patient carrying the HLA-B∗18:05 allele

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